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阴道子宫肌瘤切除术的可行性与安全性:一项前瞻性试点研究。

Feasibility and safety of vaginal myomectomy: a prospective pilot study.

作者信息

Plotti Giovanni, Plotti Francesco, Di Giovanni Alessandra, Battaglia Francesco, Nagar Giuseppe

机构信息

Department of Obstetrics and Gynecology, S. Filippo Neri Hospital of Rome, Rome, Italy.

出版信息

J Minim Invasive Gynecol. 2008 Mar-Apr;15(2):166-71. doi: 10.1016/j.jmig.2007.09.010.

Abstract

STUDY OBJECTIVE

Classic myomectomy was performed via laparotomy. More recently, laparoscopic myomectomy has become a valuable treatment option. Vaginal myomectomy is a surgical procedure that has recently been evaluated. However, few trials have been reported in past literature. The aim of this study was to evaluate feasibility and complication rate of patients submitted to vaginal myomectomy.

DESIGN

Prospective study with review of literature (Canadian Task Force classification II-2).

SETTING

Department of Obstetrics and Gynecology, S. Filippo Neri Hospital of Rome, Italy.

PATIENTS

Consecutive patients with symptomatic myomas who refused hysterectomy.

INTERVENTIONS

After preoperative assessment, patients were submitted to vaginal myomectomy using posterior colpotomy.

MEASUREMENTS AND MAIN RESULTS

Operative time, perioperative complications, and hospital stay were prospectively recorded. Follow-up examinations were performed at 1 and 12 months postoperatively. Data on possible symptoms, fertility, and pregnancy outcome during follow-up periods were recorded. Myomectomy was completed vaginally in 17 (94%) of 18 patients. Mean operating time was 48 +/- 22 minutes; mean operative blood loss and hospital stay were 210 +/- 350 mL and 3.5 +/- 2.4 days, respectively. Only 2 (11%) patients required blood transfusion. Three patients have conceived spontaneously.

CONCLUSION

Vaginal myomectomy is a feasible and safe surgical procedure, with low morbidity and short hospital stay, and could represent a valid alternative to open or laparoscopic myomectomy in selected cases.

摘要

研究目的

经典子宫肌瘤切除术通过剖腹手术进行。最近,腹腔镜子宫肌瘤切除术已成为一种有价值的治疗选择。经阴道子宫肌瘤切除术是一种最近已得到评估的外科手术。然而,过去的文献中报道的试验很少。本研究的目的是评估接受经阴道子宫肌瘤切除术患者的可行性和并发症发生率。

设计

前瞻性研究并进行文献综述(加拿大工作组分类II-2)。

地点

意大利罗马圣菲利普·内里医院妇产科。

患者

连续的有症状子宫肌瘤且拒绝子宫切除术的患者。

干预措施

术前评估后,患者采用后穹窿切开术接受经阴道子宫肌瘤切除术。

测量指标及主要结果

前瞻性记录手术时间、围手术期并发症及住院时间。术后1个月和12个月进行随访检查。记录随访期间可能出现的症状、生育能力及妊娠结局的数据。18例患者中有17例(94%)经阴道完成子宫肌瘤切除术。平均手术时间为48±22分钟;平均术中失血量和住院时间分别为210±350毫升和3.5±2.4天。仅2例(11%)患者需要输血。3例患者自然受孕。

结论

经阴道子宫肌瘤切除术是一种可行且安全的外科手术,发病率低,住院时间短,在某些特定情况下可成为开腹或腹腔镜子宫肌瘤切除术的有效替代方法。

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