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经宫腔镜切除术矫正绝经后异常子宫出血和继发性不孕女性的“峡部缺损”

Resectoscopic correction of the "isthmocele" in women with postmenstrual abnormal uterine bleeding and secondary infertility.

作者信息

Gubbini Giampietro, Casadio Paolo, Marra Elena

机构信息

"Madre Fortunata Toniolo" Clinic, Bologna, Italy.

出版信息

J Minim Invasive Gynecol. 2008 Mar-Apr;15(2):172-5. doi: 10.1016/j.jmig.2007.10.004.

Abstract

STUDY OBJECTIVE

The obstetric complications that a cesarean delivery may produce have been known and studied for a long time. In the last few years, new correlations with some gynecologic disturbances also emerged, such as postmenstrual abnormal uterine bleeding (PAUB), and with some cases of secondary infertility. This is due to the presence of a diverticulum on the anterior wall of the uterine isthmus or of the cervical canal at the site of a previous cesarean delivery scar. The aim of our study was to assess the effectiveness of a hysteroscopic surgical technique to correct this anatomic defect and therefore eliminate the symptoms.

DESIGN

A prospective study (Canadian Task Force classification III).

SETTING

Private clinic and university hospital.

PATIENTS

Twenty-six patients who previously had 1 or more cesarean deliveries, were evaluated from 2001 to 2005 for postmenstrual uterine bleeding and secondary infertility in 9 patients. All patients had a "niche" (which we defined as "isthmocele") principally on the isthmus-superior third of cervical canal (18/26), but on the lower cervical tract too (8/26). All of them underwent resectoscopic correction of the "isthmocele."

INTERVENTIONS

Hysteroscopic resection of the edges and the bottom of the defect until the complete removal of the fibrotic scar tissue showing the muscular tissue below, using a cutting loop and pure cutting current. Aimed electrocoagulation of the bottom of the pouch with a roller-ball to avoid the in situ production of blood.

MEASUREMENTS AND MAIN RESULTS

The anatomic defect in 100% of patients treated (26/26) was repaired, thus solving the symptom. Seven of 9 patients with secondary infertility became pregnant.

CONCLUSIONS

The "isthmocele" represents a possible consequence of one or more cesarean deliveries and may be symptomatic in some women. It is a defect that can be easily diagnosed by hysteroscopy and successfully treated by resectoscopic technique.

摘要

研究目的

剖宫产可能产生的产科并发症早已为人所知并得到研究。在过去几年中,还出现了与一些妇科疾病的新关联,如月经后异常子宫出血(PAUB),以及一些继发性不孕病例。这是由于在既往剖宫产瘢痕部位的子宫峡部前壁或宫颈管存在憩室。我们研究的目的是评估一种宫腔镜手术技术纠正这种解剖缺陷并消除症状的有效性。

设计

前瞻性研究(加拿大工作组分类III级)。

地点

私立诊所和大学医院。

患者

26例既往有1次或多次剖宫产的患者,于2001年至2005年接受评估,其中9例有月经后子宫出血和继发性不孕。所有患者主要在宫颈管峡部上三分之一处(18/26)有“壁龛”(我们定义为“峡部膨出”),但在下段宫颈也有(8/26)。所有患者均接受了“峡部膨出”的宫腔镜切除术。

干预措施

使用切割环和纯切割电流,对缺陷边缘和底部进行宫腔镜切除,直至完全切除显示下方肌肉组织的纤维化瘢痕组织。用滚球对囊袋底部进行靶向电凝以避免原位出血。

测量指标和主要结果

100%接受治疗的患者(26/26)的解剖缺陷得到修复,症状得以解决。9例继发性不孕患者中有7例怀孕。

结论

“峡部膨出”是一次或多次剖宫产的可能后果,在一些女性中可能出现症状。这是一种可通过宫腔镜轻松诊断并通过宫腔镜切除术成功治疗的缺陷。

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