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剖宫产瘢痕缺损所致经期中间出血女性的手术治疗及随访

Surgical treatment and follow-up of women with intermenstrual bleeding due to cesarean section scar defect.

作者信息

Fabres Cecilia, Arriagada Pablo, Fernández Carlos, Mackenna Antonio, Zegers Fernando, Fernández Emilio

机构信息

Unit of Reproductive Medicine, Department of Obstetrics and Gynecology, Clínica Las Condes, Santiago, Chile.

出版信息

J Minim Invasive Gynecol. 2005 Jan-Feb;12(1):25-8. doi: 10.1016/j.jmig.2004.12.023.

Abstract

STUDY OBJECTIVE

Previous cesarean delivery scar (PCDS) defect has been described as a cause of intermenstrual bleeding in women with no other uterine pathology except for a pouch on the anterior uterine segment at the site of the cesarean scar. The objective of this study was to assess the effectiveness of hysteroscopic surgery to correct this anatomic defect and eliminate the bleeding disturbance in a group of women with this symptom.

DESIGN

Retrospective study (Canadian Task Force classification XX).

SETTING

Private hospital, department of obstetrics and gynecology.

PATIENTS

Twenty-four women, age 29-41 years, who reported intermenstrual bleeding, especially postmenstrual spotting, with no other gynecologic pathology except for the presence of a PCDS defect. Diagnosis was established with transvaginal ultrasound, when a fluid-filled, triangular defect was seen in the anterior uterine isthmus, in relation to the cesarean section scar.

INTERVENTION

Hysteroscopic resection of fibrotic tissue that overhangs underneath the triangular pouch, facilitating blood drainage through the cervix and fulguration of endometrial glands and/or dilated blood vessels.

MEASUREMENTS AND MAIN RESULTS

The mean number of previous cesarean-section deliveries was 2.75. Postoperative follow-up was 24 months in 21 patients and at least 14 months in the other 3 patients. Eleven of these patients with the desire to become pregnant were unable to conceive after trying for a period of at least 2 years before hysteroscopy. Infertility work-up in the 11 patients revealed 9 with unknown infertility, 1 with male infertility, and 1 with failed tubal reversal surgery. Nine of them became pregnant between 14- and 24-months of follow-up. Eighty-four percent of patients (20/24) remained asymptomatic (without bleeding disturbances) after surgery.

CONCLUSION

Previous cesarean delivery scar defect may be the cause of intermenstrual bleeding, and it is possible that it also may impair fertility, but it can be successfully treated by hysteroscopic surgery.

摘要

研究目的

既往剖宫产瘢痕(PCDS)缺损被描述为除剖宫产瘢痕部位子宫前壁有一个袋状结构外无其他子宫病变的女性月经间期出血的原因。本研究的目的是评估宫腔镜手术纠正这种解剖缺陷并消除一组有此症状女性出血紊乱的有效性。

设计

回顾性研究(加拿大工作组分类XX)。

地点

私立医院妇产科。

患者

24名年龄在29 - 41岁之间的女性,她们报告有月经间期出血,尤其是月经后点滴出血,除存在PCDS缺损外无其他妇科病变。经阴道超声检查发现子宫前峡部与剖宫产瘢痕相关处有一个充满液体的三角形缺损时,确诊为此病。

干预措施

宫腔镜切除三角形袋状结构下方突出的纤维化组织,促进血液通过宫颈引流,并对子宫内膜腺体和/或扩张的血管进行电凝。

测量指标及主要结果

既往剖宫产的平均次数为2.75次。21例患者术后随访24个月,另外3例患者至少随访14个月。其中11名有怀孕意愿的患者在宫腔镜检查前尝试至少2年仍无法受孕。对这11例患者的不孕检查显示,9例原因不明,1例为男性不育,1例为输卵管复通手术失败。其中9例在随访14 - 24个月期间怀孕。84%的患者(20/24)术后无症状(无出血紊乱)。

结论

既往剖宫产瘢痕缺损可能是月经间期出血的原因,也可能影响生育,但可通过宫腔镜手术成功治疗。

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