结肠癌筛查的实施：技术、成本及障碍

Implementation of colon cancer screening: techniques, costs, and barriers.

作者信息

Miller Anthony B

机构信息

Department of Public Health Sciences, University of Toronto, 392 Lakeshore Road East, Oakville, Ontario, L6J 1J8, Canada.

出版信息

Gastroenterol Clin North Am. 2008 Mar;37(1):83-95, vi. doi: 10.1016/j.gtc.2007.12.015.

DOI:10.1016/j.gtc.2007.12.015

PMID:18313541

Abstract

Colorectal cancer and breast cancer are the only cancer sites for which evidence on the efficacy of screening is available from randomized trials. The trials on colon cancer screening in the United States and Europe used the fecal occult blood test as the primary screen, but randomized trial data are not yet available on endoscopy (flexible sigmoidoscopy to 60 cm), and no randomized, controlled trials of colonoscopy as a screening test are in progress. This article reviews colorectal cancer screening from an epidemiologist's perspective to provide the theoretic evidence-based underpinning for the role of the gastroenterologist in colorectal screening.

摘要

结直肠癌和乳腺癌是仅有的能从随机试验中获取筛查疗效证据的癌症部位。美国和欧洲关于结肠癌筛查的试验以粪便潜血试验作为主要筛查手段，但关于内镜检查（至60厘米的乙状结肠镜检查）的随机试验数据尚未可得，且目前没有正在进行的关于结肠镜检查作为筛查试验的随机对照试验。本文从流行病学家的角度回顾结直肠癌筛查，为胃肠病学家在结直肠癌筛查中的作用提供基于理论证据的支撑。