Cockerell C J
Department of Pathology (Division of Dermatopathology), University of Texas Southwestern Medical Center, Dallas.
Dermatol Clin. 1991 Jul;9(3):531-41.
Noninfectious inflammatory skin diseases are often a persistent problem for patients with infection with the human immunodeficiency virus (HIV), and they present both diagnostic and therapeutic challenges for the dermatologist. Well-defined diseases such as granuloma annulare, reactions to insect bites, and leukocytoclastic vasculitis may be more severe in these individuals and may be refractory to therapy. More poorly defined conditions with psoriasiform and papular morphologies have also been described. A number of skin conditions, including pityriasis rubra pilaris, cutaneous T-cell lymphoma, and erythema elevatum diutinum, have recently been observed in the HIV-infected host. Because the dermatologist plays an important role in diagnosis and management of patients with HIV infection, it is important that he or she be well versed in the clinical manifestations and natural history of these conditions.
对于感染人类免疫缺陷病毒（HIV）的患者而言，非感染性炎性皮肤病常常是一个持续存在的问题，并且它们给皮肤科医生带来了诊断和治疗方面的挑战。诸如环状肉芽肿、蚊虫叮咬反应和白细胞破碎性血管炎等明确的疾病在这些个体中可能更为严重，并且可能对治疗无效。也有一些定义不太明确的具有银屑病样和丘疹形态的病症被描述过。最近在HIV感染宿主中观察到了许多皮肤疾病，包括毛发红糠疹、皮肤T细胞淋巴瘤和持久性隆起性红斑。由于皮肤科医生在HIV感染患者的诊断和管理中起着重要作用，因此他或她熟悉这些病症的临床表现和自然病史非常重要。
