Haliloglu N U, Yesilirmak Z, Erden A, Erden I
University of Ankara, Faculty of Medicine, Department of Radiology, Ibni Sina Hospital, 06100 Ankara, Turkey.
Dentomaxillofac Radiol. 2008 Mar;37(3):161-6. doi: 10.1259/dmfr/14698002.
Rhino-orbito-cerebral mucormycosis (ROCM) is a rare, fulminant opportunistic fungal infection that is mostly seen in immunocompromised or diabetic patients. The disease should be recognised and treated immediately. We present here MR imaging findings of two patients with histopathologically proven ROCM. One of the cases had a history of corticosteroid treatment and iatrogenic diabetes mellitus and although amphotericin B was started immediately, the disease progressed and surgical debridement was necessary. The second case was a patient with diabetes mellitus type 1 in whom ROCM had occurred following an abdominal surgery; amphotericin B treatment alone was adequate in this patient.
鼻眶脑毛霉菌病（ROCM）是一种罕见的、暴发性机会性真菌感染，多见于免疫功能低下或糖尿病患者。该病应立即得到识别和治疗。我们在此展示两例经组织病理学证实为ROCM患者的磁共振成像（MR）表现。其中一例有皮质类固醇治疗史和医源性糖尿病，尽管立即开始使用两性霉素B，但病情仍进展，需要进行手术清创。第二例是一名1型糖尿病患者，在腹部手术后发生了ROCM；该患者单独使用两性霉素B治疗就足够了。
