Jia N
PUMC Hospital, Beijing.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1991 Apr;13(2):112-4.
To investigate the stress-response during anesthesia-operation, 16 patients were allocated into either of two groups. Eight cases in Group A underwent an operation on the abdomen under general anesthesia, while the other eight cases in Group B were operated under general anesthesia plus epidural block. Plasma catecholamine levels were measured in all subjects during anesthesia operation procedure. A significant increase in the levels of plasma catecholamines was observed at 45 min after incision in Group A (1.82 +/- 0.48 vs. 0.94 +/- 0.19 ng/ml, P less than 0.05, paired t-test), while no change was seen in Group B during the whole procedure. The result may indicate that an operation on the abdomen rather than general anesthesia itself is responsible for the observed increase in plasma catecholamines level.
为研究麻醉手术期间的应激反应，将16例患者分为两组。A组8例患者在全身麻醉下进行腹部手术，而B组另外8例患者在全身麻醉加硬膜外阻滞下进行手术。在麻醉手术过程中测量所有受试者的血浆儿茶酚胺水平。A组在切开后45分钟时观察到血浆儿茶酚胺水平显著升高（1.82±0.48 vs. 0.94±0.19 ng/ml，配对t检验，P<0.05），而B组在整个过程中未见变化。结果可能表明，是腹部手术而非全身麻醉本身导致了观察到的血浆儿茶酚胺水平升高。
