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[林县腌制蔬菜与食管癌病因的研究。II. 亚硝胺及其前体的测定]

[Studies of pickled vegetables and cause of esophageal cancer in Linxian. II. Determination of nitrosamines and their precursors].

作者信息

Ji C, Li M

机构信息

Institute of Oncology, Beijing.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1991 Jun;13(3):230-2.

PMID:1831733
Abstract

Pickled vegetables are daily food consumed in the high-risk areas for esophageal cancer in China. We analyzed the nitrosamine content of Linxian pickles by GC/TEA and found that trace amounts of six nitrosamines (NDMA, NDEA, NMBA, NMAMBA, NDPA, NPYR) were present, with the highest concentrations being NDMA and NDEA (1.7 and 1.9 micrograms/kg wet weight respectively). The average level of nitrosamine precursors, such as nitrate (111.22 mg/L), nitrite (0.152 mg/L) and secondary amines (4.223 mg/L), in pickled vegetables were determined, and their pH values ranged from 3 to 5.

摘要

泡菜是中国食管癌高发地区的日常食用食物。我们采用气相色谱/热离子发射检测器(GC/TEA)分析了林县泡菜中的亚硝胺含量,发现其中含有痕量的六种亚硝胺(N-亚硝基二甲胺、N-亚硝基二乙胺、N-亚硝基甲基苄胺、N-亚硝基甲基苯并[a]芘、N-亚硝基哌啶、N-亚硝基吡咯烷),其中含量最高的是N-亚硝基二甲胺和N-亚硝基二乙胺(湿重分别为1.7微克/千克和1.9微克/千克)。测定了泡菜中亚硝胺前体物质如硝酸盐(111.22毫克/升)、亚硝酸盐(0.152毫克/升)和仲胺(4.223毫克/升)的平均含量,其pH值范围为3至5。

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