Launay-Vacher Vincent, Rey Jean-Baptiste, Isnard-Bagnis Corinne, Deray Gilbert, Daouphars Mikael
ICAR, Department of Nephrology, Hôpital Pitié-Salpêtrière, 83 boulevard de l'Hôpital, 75013 Paris, France.
Cancer Chemother Pharmacol. 2008 May;61(6):903-9. doi: 10.1007/s00280-008-0711-0. Epub 2008 Mar 4.
Antineoplastic drugs used in the treatment of cancers present with variable renal tolerance profiles. Among drugs with a potential for renal toxicity, platinum salts, and especially cisplatin is a well-known agent that may induce acute and chronic renal failure. The mechanisms of its renal toxicity and the means of its prevention are presented in this article which represent the Clinical Recommendation from the Special Interest Group on Cancer Care of the European Society of Clinical Pharmacy (ESCP).
用于治疗癌症的抗肿瘤药物具有不同的肾脏耐受性特征。在有潜在肾毒性的药物中，铂盐，尤其是顺铂，是一种众所周知的可导致急性和慢性肾衰竭的药物。本文介绍了其肾毒性机制及预防方法，这些内容代表了欧洲临床药学学会（ESCP）癌症护理特别兴趣小组的临床建议。
