Narita Yusuke, Naoki Katsuhiko, Hida Naoya, Okamoto Hiroaki, Kunikane Hiroshi, Omori Takahiro, Kase Masahiro, Watanabe Koshiro
Department of Respiratory Medicine, Yokohama Municipal Citizens' Hospital.
Nihon Kokyuki Gakkai Zasshi. 2008 Feb;46(2):120-5.
A 20-year-old woman, with systemic lupus erythmatosus complicated by steroid-and immunosuppressant-resistant bilateral pleural effusion, was admitted to the emergency room because of dyspnea and fever. Chest Xray film revealed bilateral massive pleural effusion. Bilateral thoracocentesis yielded fluid with chyle. Conservative treatment including intravenous hyper-alimentation and continuous drainage were performed but with no remarkable improvement. She underwent thoracoscopy-aided ligation of the thoracic duct. After the operation, bilateral pleurodesis was performed by intrathoracic injection of OK-432, because of uncontrolled pleural effusion. There have been no signs of recurrence at 10 months in this case of SLE with steroid-and immunosuppressant-resistant pleural effusion.
一名20岁女性，患有系统性红斑狼疮，并发对类固醇和免疫抑制剂耐药的双侧胸腔积液，因呼吸困难和发热入住急诊室。胸部X光片显示双侧大量胸腔积液。双侧胸腔穿刺抽出乳糜样液体。进行了包括静脉高营养和持续引流在内的保守治疗，但无明显改善。她接受了胸腔镜辅助下胸导管结扎术。术后，由于胸腔积液无法控制，通过胸腔内注射OK-432进行了双侧胸膜固定术。在这例对类固醇和免疫抑制剂耐药的系统性红斑狼疮胸腔积液患者中，术后10个月无复发迹象。
