Krathen M, Treat J, James W D
Department of Dermatology, Hospital of University of Pennsylvania, Philadelphia, USA.
Dermatol Online J. 2007 Oct 13;13(4):13.
Capecitabine, an oral prodrug of 5-fluorouracil, is a systemic chemotherapeutic agent used in the treatment of metastatic breast and colon cancer. Patients undergoing capecitabine therapy may experience inflammation and irritation of existing actinic keratoses. Oncologists and dermatologists alike should be aware of this side effect.