Higa Gerald M, Kovach Rodney F, Abraham Jame
Department of Medicine, Section of Hematology/Oncology, West Virginia University, Morgantown, USA.
J Oncol Pharm Pract. 2005 Dec;11(4):151-3. doi: 10.1191/1078155205jp163cr.
Topical application of 5-fluorouracil (5-FU) is one of the most effective clinical strategies available to treat actinic keratosis (AK). During treatment, an apparent toxic skin reaction occurs before dermal quiescence ensues. We report a case of a typical flare of AK in a woman treated with capecitabine for advanced breast cancer.