Okano Yoshio, Inayama Mami, Hatakeyama Nobuo, Hino Hiroyuki, Iwahara Yoshito, Motoki Tokuji, Naruse Keishi, Yokota Yoshio, Ogushi Fumitaka
Departments of Respiratory Medicine, National Hospital Organization, Kochi Hospital, Kochi, Japan.
J Med Invest. 2008 Feb;55(1-2):142-6. doi: 10.2152/jmi.55.142.
We report an autopsy case of rapid progressive atypical carcinoid of the lung discovered as multiple nodular shadows. The patient was an 82-year-old man with non-productive cough. Both chest radiography and computed tomography revealed multiple nodules in both the lung and pleural effusion. Multiple metastases to bone and liver were also noted. Samples from the wall-side pleural lesion were obtained by video-assisted thoracoscopic surgery under local anesthesia, and histological examination led to a diagnosis of atypical carcinoid. Treatment was ineffective and the patient died on day 39 after admission. The primary site was identified as the lung after autopsy. We believe that early detection is crucial in the treatment of atypical carcinoid due to poor prognosis.
我们报告一例以多发结节状阴影发现的肺快速进展性非典型类癌的尸检病例。患者为一名82岁男性,有干咳症状。胸部X线摄影和计算机断层扫描均显示肺部有多发结节及胸腔积液。还发现有骨和肝的多发转移。在局部麻醉下通过电视辅助胸腔镜手术获取壁侧胸膜病变的样本,组织学检查诊断为非典型类癌。治疗无效,患者在入院后第39天死亡。尸检后确定原发部位为肺。我们认为,由于预后较差,早期发现对非典型类癌的治疗至关重要。