Gad El-Moula Mohamed, Izaki Hirofumi, El-Anany Fathy, Abd El-Moneim Alaa, El-Moneim El-Haggagy Abd, Abdelsalam Yasser, Abolyosr Ahmad, Kishimoto Tomoteru, Oka Natsuo, Takahashi Masayuki, Fukumori Tomoharu, Kanayama Hiro-Omi
Department of Urology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.
J Med Invest. 2008 Feb;55(1-2):147-50. doi: 10.2152/jmi.55.147.
From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results.
1999年5月至2006年8月,我们对103例隐睾患者进行了腹腔镜诊断与治疗。其中,我们发现了5例不同病因的男性假两性畸形。3例男性表现为隐睾伴生殖器模糊,2例女性表现为原发性闭经。他们均具有46-XY正常男性染色体核型。前3例病因是完全性性腺发育不全,2例是持续性苗勒管综合征。对第1例进行了择期性腺切除术,对另外2例进行了腹腔镜睾丸固定术。另外2例女性患者的病因是完全性雄激素不敏感综合征,均对其进行了腹腔镜双侧睾丸切除术。所有手术均无并发症,效果满意。