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腹腔镜检查与两性畸形:5例男性假两性畸形病例报告

Laparoscopy and intersex: report of 5 cases of male pseudohermaphroditism.

作者信息

Gad El-Moula Mohamed, Izaki Hirofumi, El-Anany Fathy, Abd El-Moneim Alaa, El-Moneim El-Haggagy Abd, Abdelsalam Yasser, Abolyosr Ahmad, Kishimoto Tomoteru, Oka Natsuo, Takahashi Masayuki, Fukumori Tomoharu, Kanayama Hiro-Omi

机构信息

Department of Urology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan.

出版信息

J Med Invest. 2008 Feb;55(1-2):147-50. doi: 10.2152/jmi.55.147.

Abstract

From May, 1999 to August, 2006, we performed laparoscopic diagnosis and treatment for 103 cases of impalpable testes. Among those we found 5 cases of male pseudohermaphroditism of different etiologies. Three males presented by impalpable testes with ambiguous genitalia and 2 females presented by primary amenorrhea. All of them have 46-XY normal male chromosomal pattern. In the first 3 cases, the etiology was complete gonadal dysgenesis, and 2 cases with persistent Mullerian syndrome. Timed gonadectomy for the first case and laparoscopic orchiopexy for the other 2 cases were performed. For the other 2 female cases, the etiology was complete androgen insensitivity syndrome and laparoscopic bilateral orchiectomy was performed for both of them. All the procedures were done without complications with satisfactory results.

摘要

1999年5月至2006年8月,我们对103例隐睾患者进行了腹腔镜诊断与治疗。其中,我们发现了5例不同病因的男性假两性畸形。3例男性表现为隐睾伴生殖器模糊,2例女性表现为原发性闭经。他们均具有46-XY正常男性染色体核型。前3例病因是完全性性腺发育不全,2例是持续性苗勒管综合征。对第1例进行了择期性腺切除术,对另外2例进行了腹腔镜睾丸固定术。另外2例女性患者的病因是完全性雄激素不敏感综合征,均对其进行了腹腔镜双侧睾丸切除术。所有手术均无并发症,效果满意。

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