可生物降解支架

Biodegradable stents.

作者信息

Ramcharitar S, Serruys P W

机构信息

Department of Interventional, Cardiology Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands

出版信息

Minerva Cardioangiol. 2008 Apr;56(2):205-13.

PMID:18319699

Abstract

Bioabsorbable stents must be biocompatible and as well as their degenerated products. The challenge is to find material that exhibit minimal recoil and remain in situ for several months before complete bio-absorption. There are now some worthy polymer based and metallic bioabsorbable stents with encouraging preclinical and clinical data. Their behaviour will not only redefine current percutaneous coronary intervention but may also have a wider role in the cardiovascular system as whole.

摘要

生物可吸收支架及其降解产物必须具有生物相容性。挑战在于找到一种材料，这种材料在完全生物吸收前能表现出最小的回缩并在原位留存数月。目前有一些基于聚合物和金属的值得关注的生物可吸收支架，其临床前和临床数据令人鼓舞。它们的性能不仅将重新定义当前的经皮冠状动脉介入治疗，还可能在整个心血管系统中发挥更广泛的作用。