Regis Dario, Corallo Fabio, Franchini Massimo, Rosa Raffaella, Ricci Matteo, Bartolozzi Pietro
Department of Orthopaedic Surgery, University Hospital of Verona, Verona, Italy.
Chir Organi Mov. 2008 Jan;91(1):41-4. doi: 10.1007/s12306-007-0007-2. Epub 2008 Feb 10.
Preoperative autologous blood donation (PABD) is a well established transfusion practice in elective orthopaedic surgery, involving immunologic and infective advantages but also involving exposure to not negligible risks, and costs as well. The aim of this study was to assess the real need for blood transfusions in primary total knee arthroplasty (TKA). Between January 2000 and July 2005, 214 patients underwent primary unilateral TKA. Altogether, 416 autologous blood units were collected, however only 47 (11.3%) were transfused. Thirty-eight patients (17.8%) received autologous blood, while 4 of them (10.5%) also received allogeneic blood. Based on the results of this study, PABD should be recommended in well selected patients undergoing TKA: older female patients with a low basal haemoglobin level.
术前自体血捐献（PABD）在择期骨科手术中是一种成熟的输血方式，具有免疫和感染方面的优势，但也存在不可忽视的风险及成本。本研究的目的是评估初次全膝关节置换术（TKA）中输血的实际需求。2000年1月至2005年7月期间，214例患者接受了初次单侧TKA。总共采集了416单位自体血，但仅47单位（11.3%）被输注。38例患者（17.8%）接受了自体血，其中4例（10.5%）还接受了异体血。基于本研究结果，对于精心挑选的接受TKA的患者，即基础血红蛋白水平较低的老年女性患者，应推荐采用PABD。
