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[重新评估肝衰竭的临床分类标准]

[To re-evaluate the clinical classification criteria of liver failure].

作者信息

Zeng Zhen, Lou Min, Han Yu-kun, Geng Hua, Chang Xiu-juan, Chen Ju-mei

机构信息

The 302 Hospital of PLA, Beijing, 100039 China.

出版信息

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2007 Dec;21(4):377-9.

Abstract

OBJECTIVE

To study the clinical feature and more reasonable diagnostic typing criteria for patients with liver failure.

METHODS

13/21 cases of ALF, SALF with no past liver disease, 49/72 cases of with chronic hepatitis, and 23/73 cases ALF, SALF with liver cirrhosis, were analyzed respectively.

RESULTS

1 ALF patients (1). There exist significant statistic differences in ALB, ALT, CHE in three ALF groups.(2). It had statistic differences in those patients with hepatic encephalopathy.(3). The prognosis of the patients with chronic hepatitis group (42.85 percent) was best than that of chronic cirrhosis (26.09 percent) and no past liver disease (15.38 percent). (2) In SALF patients (1). There exist significant statistic differences in ALB, GLO, ALT, AST, BDIL, GLU and CHE in three SALF groups.(2). It had statistic differences in those patients with hepatic encephalopathy in three SALF groups.(3). The prognosis of the patients with chronic hepatitis group (51.39 percent) was best than that of chronic cirrhosis (36.85 percent) and no past liver disease (33.33 percent).

CONCLUSION

There are different clinic feature and prognosis in three ALF or SALF groups, so we suggest that it were clinic practicability and science in classify of liver failure at present.

摘要

目的

研究肝衰竭患者的临床特征及更合理的诊断分型标准。

方法

分别分析了21例急性肝衰竭(ALF)、无既往肝病的亚急性肝衰竭(SALF)患者中的13例,72例慢性肝炎患者中的49例,以及73例肝硬化患者中的23例ALF、SALF患者。

结果

(1)ALF患者:①三个ALF组在白蛋白(ALB)、谷丙转氨酶(ALT)、胆碱酯酶(CHE)方面存在显著统计学差异。②肝性脑病患者存在统计学差异。③慢性肝炎组患者的预后(42.85%)优于慢性肝硬化组(26.09%)和无既往肝病组(15.38%)。(2)SALF患者:①三个SALF组在ALB、球蛋白(GLO)、ALT、谷草转氨酶(AST)、直接胆红素(BDIL)、葡萄糖(GLU)和CHE方面存在显著统计学差异。②三个SALF组中肝性脑病患者存在统计学差异。③慢性肝炎组患者的预后(51.39%)优于慢性肝硬化组(36.85%)和无既往肝病组(33.33%)。

结论

三个ALF或SALF组有不同的临床特征和预后,因此我们认为目前肝衰竭的分类具有临床实用性和科学性。

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