Interactions in free radicals processes between cyclosporine A and sodium fluoride.

The interactions in free radicals processes between cyclosporine A (CsA) and sodium fluoride (NaF) on in vitro model human placental mitochondria were evaluated. The level of malondialdehyde, hydroxyl radical generation and concentration of sulfhydryl groups of protein was measured. The results showed that CsA with NaF did not give any toxicological interactions with NaF in the area of measured parameters.