湿热处理的高直链玉米淀粉对高胆固醇血症大鼠血清胆固醇的降低作用。

Serum cholesterol-decreasing effect of heat-moisture-treated high-amylose cornstarch in cholesterol-loaded rats.

作者信息

Udagawa Haruhide, Kitaoka Chika, Sakamoto Tatsuaki, Kobayashi-Hattori Kazuo, Oishi Yuichi, Arai Soichi, Takita Toshichika

机构信息

Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Tokyo 156-8502, Japan.

出版信息

Biosci Biotechnol Biochem. 2008 Mar;72(3):880-4. doi: 10.1271/bbb.70656. Epub 2008 Mar 7.

DOI:10.1271/bbb.70656

PMID:18323668

Abstract

Rats were fed on a diet containing cholesterol (Chol) at a level corresponding to the standard Chol intake in humans, and the influence of heat-moisture-treated high-amylose cornstarch (HHA) on their serum Chol level was investigated. HHA decreased the serum level of Chol in rats fed on the diet containing 0.1% Chol, which corresponds to a Chol intake in humans of 800 mg/d, although the liver levels of Chol increased in these rats. HHA did not influence the fecal excretion of Chol/bile acids. It is possible that the decrease in serum Chol level in the rats fed on the high-Chol diet can be attributed to the promotion of Chol uptake in the liver.

摘要

给大鼠喂食含有与人类标准胆固醇摄入量相当水平胆固醇（Chol）的饮食，并研究热湿处理的高直链玉米淀粉（HHA）对其血清胆固醇水平的影响。HHA降低了喂食含0.1%Chol饮食的大鼠的血清胆固醇水平，这相当于人类每天摄入800mg胆固醇，尽管这些大鼠肝脏中的胆固醇水平有所升高。HHA不影响胆固醇/胆汁酸的粪便排泄。喂食高胆固醇饮食的大鼠血清胆固醇水平降低可能归因于肝脏中胆固醇摄取的促进。