Groeneveld Susanne, Verweij Paul E, Hek Louis Van't, Bökkerink Jos P M, Warris Adilia
Department of Pediatrics, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
Med Mycol. 2008 Mar;46(2):185-7. doi: 10.1080/13693780701658280.
Due to the similarity of their generic names, the use of amphotericin B-deoxycholate and liposomal amphotericin B could cause confusion in daily practice. We report two cases of amphotericin B-deoxycholate overdose in infants due to administration errors which raises the issue that the use of this antifungal agent should be questioned because of its severe side effects.
由于两性霉素B脱氧胆酸盐和两性霉素B脂质体的通用名相似,在日常实践中使用它们可能会造成混淆。我们报告了两例因用药错误导致婴儿两性霉素B脱氧胆酸盐过量的病例,这引发了一个问题,即鉴于其严重的副作用,这种抗真菌药物的使用应该受到质疑。