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坚持标准化心力衰竭核心措施带来的生存获益增量:一项对2958例患者的绩效评估研究

Incremental survival benefit with adherence to standardized heart failure core measures: a performance evaluation study of 2958 patients.

作者信息

Kfoury Abdallah G, French Thomas K, Horne Benjamin D, Rasmusson Kismet D, Lappé Donald L, Rimmasch Holly L, Roberts Colleen A, Evans R Scott, Muhlestein Joseph B, Anderson Jeffrey L, Renlund Dale G

机构信息

Heart Failure Prevention and Treatment Program, Intermountain Medical Center and Intermountain Healthcare, 5121 S Cottonwood Street, Murray, UT 84107, USA.

出版信息

J Card Fail. 2008 Mar;14(2):95-102. doi: 10.1016/j.cardfail.2007.10.011.

Abstract

BACKGROUND

In 2002, the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) established four heart failure (HF) core measures to standardize and improve health care quality in the United States. Although adherence to these HF care processes may be improving, their collective impact on survival is not yet settled.

METHODS

JCAHO HF measures were implemented within a 20-hospital health care system. Eligible patients had a principal discharge diagnosis of HF. Metrics representing compliance with these measures were derived and their relationship with 1-year survival was examined using an adjusted Cox proportional hazards regression.

RESULTS

A total of 2958 patients met study criteria. The average age was 73 years, 50% were male, and 9.9% were smokers. One-year survival benefits were seen in an item-by-item evaluation of HF measures for angiotensin-converting enzyme inhibitor/angiotensin receptor blocker therapy (hazard ratio [HR] = 0.69), left ventricular function assessment (HR = 0.83), and patient education (HR = 0.79). When assessed collectively, improved survival was seen among patients eligible for two (HR = 0.53), three (HR = 0.36), or four HF measures (HR = 0.65). Further, we found a positive and incremental relationship between the degree of adherence and survival (P = .008).

CONCLUSION

Adherence to JCAHO HF core measures is associated with improved 1-year survival after HF hospitalization. This validates these simple and effective performance measures and justifies efforts to implement them in all eligible patients with HF.

摘要

背景

2002年,医疗保健机构认证联合委员会(JCAHO)制定了四项心力衰竭(HF)核心措施,以规范和提高美国的医疗质量。尽管对这些HF护理流程的依从性可能正在改善,但其对生存率的总体影响尚未明确。

方法

在一个拥有20家医院的医疗系统中实施JCAHO HF措施。符合条件的患者主要出院诊断为HF。得出代表对这些措施依从性的指标,并使用校正后的Cox比例风险回归分析其与1年生存率的关系。

结果

共有2958名患者符合研究标准。平均年龄为73岁,50%为男性,9.9%为吸烟者。在对HF措施进行逐项评估时,血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂治疗(风险比[HR]=0.69)、左心室功能评估(HR=0.83)和患者教育(HR=0.79)方面,观察到1年生存获益。综合评估时,符合两项(HR=0.53)、三项(HR=0.36)或四项HF措施的患者生存率提高(HR=0.65)。此外,我们发现依从程度与生存率之间存在正相关且呈递增关系(P=0.008)。

结论

坚持JCAHO HF核心措施与HF住院后1年生存率提高相关。这验证了这些简单有效的绩效指标,并证明了在所有符合条件的HF患者中实施这些措施的努力是合理的。

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