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基于病例的运动和神经精神疾病中脑深部电刺激器问题故障排除综述。

A case-based review of troubleshooting deep brain stimulator issues in movement and neuropsychiatric disorders.

作者信息

Okun Michael S, Rodriguez Ramon L, Foote Kelly D, Sudhyadhom Atchar, Bova Frank, Jacobson Charles, Bello Brian, Zeilman Pamela, Fernandez Hubert H

机构信息

Department of Neurology and Neurosurgery, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL 32610, USA.

出版信息

Parkinsonism Relat Disord. 2008 Nov;14(7):532-8. doi: 10.1016/j.parkreldis.2008.01.001. Epub 2008 Mar 5.

Abstract

OBJECTIVE

To review the spectrum of problems that can occur in the DBS patient and to suggest potential troubleshooting tips for identification and management of DBS related issues.

BACKGROUND

Deep brain stimulation (DBS) has become commonplace for the treatment of medication-refractory neurological disorders. There remains no consensus on the best practices for screening, surgical techniques, and post-operative care. There are few experienced DBS programmers and scarce resources available describing approaches for troubleshooting DBS problems.

METHODS

We present a case-based review that offers practical tips for the management and troubleshooting of difficult to manage DBS cases. We present 10 cases to demonstrate common issues encountered in DBS management.

RESULTS

There are many important difficulties that may be encountered with DBS devices, and practitioners should be aware of these potential problems, as well as rational management solutions. The following areas should be emphasized as potential causes of difficulties: a non-ideal initial DBS candidate, inadequate multidisciplinary team care, failure of perceived expectations, DBS procedural complication, hardware complication, suboptimal lead placement, programming, access to care, disease progression, and tolerance/habituation.

CONCLUSION

Neurologists seeing DBS patients should become familiar with issues involved in difficult to manage DBS cases. Many "DBS failures" are currently treatable by appropriate medicine, programming, and surgical approaches.

摘要

目的

回顾脑深部电刺激(DBS)患者可能出现的一系列问题,并提出识别和处理与DBS相关问题的潜在故障排除技巧。

背景

脑深部电刺激已成为治疗药物难治性神经疾病的常用方法。在筛查、手术技术和术后护理的最佳实践方面尚未达成共识。经验丰富的DBS程控师很少,且描述DBS问题故障排除方法的资源稀缺。

方法

我们进行了一项基于病例的综述,为处理难以管理的DBS病例提供实用技巧。我们展示了10个病例,以说明DBS管理中遇到的常见问题。

结果

DBS设备可能会遇到许多重要困难,从业者应了解这些潜在问题以及合理的管理解决方案。以下方面应被视为困难的潜在原因:初始DBS候选人不理想、多学科团队护理不足、预期未达成、DBS手术并发症、硬件并发症、电极放置欠佳、程控、获得医疗服务、疾病进展以及耐受性/适应性。

结论

诊治DBS患者的神经科医生应熟悉处理难以管理的DBS病例所涉及的问题。目前,许多“DBS失败”情况可通过适当的药物、程控和手术方法进行治疗。

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