Deluca Cristina, Tommasi Giorgio, Moretto Giuseppe, Fiaschi Antonio, Tinazzi Michele
Dipartimento di Scienze Neurologiche e della Visione, Università di Verona, Piazzale Scuro 9, 37134 Verona, Italy.
Parkinsonism Relat Disord. 2008 Dec;14(8):649-51. doi: 10.1016/j.parkreldis.2007.12.005. Epub 2008 Mar 5.
A young female patient, who presented acutely with an unusual movement disorder characterized by hyperkinetic facial movements, was referred to us for hemifacial spasm. The only abnormality on neurological examination was myoclonus of the left perioral and bilateral periorbital muscles, exacerbated by mental tasks. A week later, the patient also presented two generalized tonic-clonic seizures on awakening and was successfully treated with antiepileptic drugs. Laboratory and neuroimaging investigations yielded normal findings. Although we were unable to identify a cortical generator, the concomitant occurrence of generalized seizures, the disappearance of symptoms after treatment and the topography of the myoclonus support an epileptic origin of this myoclonus.
一名年轻女性患者急性就诊，表现为以面部运动亢进为特征的异常运动障碍，因半面痉挛被转诊至我院。神经系统检查唯一的异常是左侧口周和双侧眶周肌肉的肌阵挛，在精神任务时加重。一周后，患者醒来时还出现了两次全身性强直阵挛发作，并成功接受了抗癫痫药物治疗。实验室和神经影像学检查结果均正常。尽管我们无法确定皮质起源，但全身性癫痫发作的同时出现、治疗后症状的消失以及肌阵挛的部位支持了这种肌阵挛的癫痫起源。
