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[治疗期间儿童胸内淋巴结结核特异性致敏反应及其他免疫参数的评估]

[Estimation of the specific sensitization in a child and other immunological parameters in tuberculosis of intrathoracic lymph nodes during therapy].

作者信息

efremova S N, Dovgaliuk I F, Sakharova I Ia

出版信息

Probl Tuberk Bolezn Legk. 2007(12):22-5.

PMID:18326210
Abstract

The data of a comprehensive study of 86 children aged 6 to 14 years, who were examined and treated at the Research Institute of Phthisiology for various manifestations of tuberculous infection: 25.6% with infected Mycobacterium tuberculosis with varying specific sensitization; 34.9% with minor forms of intrathoracic lymph node tuberculosis (ILNT), and 39.5% with disseminated processes into the intrathoracic lymph nodes. RM V, VI, VII, and VIII dilutions are of the greatest informative value in the determination of the activity of tuberculous infection. Most children with ILNT showed a significant cellular response to PPD in the LBT test, The LCT test revealed that neutrophilic granulocytes were functionally inadequate in all the children. The currently available immunological tests used in combination with the existing methods adequately evaluate the activity of tuberculous infection in children.

摘要

对86名6至14岁儿童进行综合研究的数据,这些儿童在结核病研究所接受了检查和治疗,患有各种结核感染表现:25.6%感染结核分枝杆菌且有不同程度的特异性致敏;34.9%患有轻度胸内淋巴结结核(ILNT),39.5%患有胸内淋巴结播散性病变。RM V、VI、VII和VIII稀释度在确定结核感染活动方面具有最大的信息价值。大多数ILNT儿童在LBT试验中对PPD有显著的细胞反应,LCT试验显示所有儿童的中性粒细胞功能不足。目前可用的免疫学检测与现有方法结合可充分评估儿童结核感染的活动情况。

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