van der Jagt M, Bosman R J, van Schaik I N, van der Bilt I A C, Dekker L R, Zandstra D F
Afd. Intensive Care, Onze Lieve Vrouwe Gasthuis, Amsterdam.
Ned Tijdschr Geneeskd. 2008 Feb 9;152(6):297-301.
Three case studies illustrate that suspected anoxic-ischaemic coma often requires careful differential diagnosis to detect treatable conditions. A 47-year-old man underwent cardiopulmonary resuscitation for ventricular fibrillation caused by myocardial ischaemia. He exhibited rhythmic eyelid movements while in a coma. Epilepsy was suspected, and the patient regained consciousness after being treated with antiepileptic drugs. A 34-year-old man underwent cardiopulmonary resuscitation for multiple episodes of ventricular fibrillation. Treatment was directed toward myocardial ischaemia and included anticoagulants. The patient had bilateral, fixed dilated pupils. A CT of the brain showed traumatic contrecoup haemorrhage in the left temporal lobe with signs of transtentorial herniation. The patient died. A 74-year-old woman was found unconscious at home. An ECG performed by the paramedics showed ST segment elevation in the precordial leads. Anoxic-ischaemic coma following cardiac arrest was suspected. However, a coronary angiogram was normal and a CT of the brain revealed subarachnoid haemorrhage caused by a ruptured intracranial aneurysm. She recovered after cranial surgery.
三个案例研究表明,疑似缺氧缺血性昏迷通常需要仔细的鉴别诊断以检测出可治疗的病症。一名47岁男性因心肌缺血导致心室颤动而接受心肺复苏。他在昏迷时出现有节律的眼睑运动。怀疑为癫痫,患者在接受抗癫痫药物治疗后恢复意识。一名34岁男性因多次心室颤动发作而接受心肺复苏。治疗针对心肌缺血,包括使用抗凝剂。该患者双侧瞳孔固定散大。脑部CT显示左颞叶有创伤性对冲性出血并有小脑幕切迹疝的迹象。患者死亡。一名74岁女性在家中被发现昏迷。护理人员进行的心电图显示胸前导联ST段抬高。怀疑为心脏骤停后的缺氧缺血性昏迷。然而,冠状动脉造影正常,脑部CT显示由颅内动脉瘤破裂引起的蛛网膜下腔出血。她在接受开颅手术后康复。