Radulescu Dan, Pripon Sorin, Duncea Caius, Constantea Nicolae A, Gulei Iulia
Cardiology Department, 5th Medical Clinic, Municipal Hospital, Romania.
Acta Med Indones. 2008 Jan;40(1):24-8.
to estimate the comparative value of conventional radiology and cardiac catheterization in establishing the diagnosis and severity of primary and secondary pulmonary hypertension. We also tried to achieve some correlations between the radiological and invasive parameters.
we performed a retrospective study over an 11-years time period, analyzing data from a group of 14 patients diagnosed with primary pulmonary hypertension compared to a matched group of 20 patients suffering from pulmonary hypertension secondary to mitral and aortic valvular disease. All the patients had undergone conventional radiology (chest X-ray) and catheterization of the right heart cavities and pulmonary artery.
we detected significantly elevated pulmonary artery pressures and resistances in the primary pulmonary hypertension group compared to secondary hypertension patients. Cardiac output values were much lower in the primary pulmonary hypertension individuals compared with secondary pulmonary hypertension in left-sided valvular disease. The pulmonary artery arch diameter, the diameter of the right descending pulmonary artery and the value of the arterio-bronchial ratio were similar in the two groups.
in both groups, we found a statistically significant positive correlation between the values of the pulmonary artery vascular resistance and the diameter of the right descending pulmonary artery, which are very specific parameters in the diagnosis of pulmonary hypertension. In the primary pulmonary hypertension group we identified a significant inverse correlation between the diameter of the right descending pulmonary artery and the values of cardiac output. This finding was not confirmed in the secondary group.
评估传统放射学检查和心导管检查在诊断原发性和继发性肺动脉高压及其严重程度方面的比较价值。我们还试图找出放射学参数和侵入性参数之间的一些相关性。
我们进行了一项为期11年的回顾性研究,分析了一组14例诊断为原发性肺动脉高压患者的数据,并与一组20例继发于二尖瓣和主动脉瓣疾病的肺动脉高压患者进行匹配对照。所有患者均接受了传统放射学检查(胸部X光)以及右心腔和肺动脉导管检查。
与继发性高血压患者相比,我们发现原发性肺动脉高压组的肺动脉压力和阻力显著升高。原发性肺动脉高压患者的心输出量值明显低于左侧瓣膜病继发性肺动脉高压患者。两组的肺动脉弓直径、右下肺动脉直径和动支气管比值相似。
在两组中,我们发现肺动脉血管阻力值与右下肺动脉直径之间存在统计学上显著的正相关,这是诊断肺动脉高压的非常特异的参数。在原发性肺动脉高压组中,我们发现右下肺动脉直径与心输出量值之间存在显著的负相关。在继发性组中未证实这一发现。