Robles David T, Moore Erin, Draznin Michelle, Berg Daniel
Department of Medicine, Division of Dermatology, University of Washington Medical Center, Seattle, USA.
Dermatol Online J. 2007 Jul 13;13(3):9.
Keloid formation occurs as a result of abnormal wound healing. Despite the high prevalence of keloids in the general population, they remain one of the more challenging dermatologic conditions to manage. More than a cosmetic nuisance, they are often symptomatic and can have a significant psychosocial burden for the patient. Although multiple treatment modalities exist, no single treatment has proven widely effective. In fact, recurrence following treatment is generally the norm. Combination therapy is likely the optimal strategy. In this review, we highlight the clinical features, pathophysiology and management of keloids.
瘢痕疙瘩的形成是伤口异常愈合的结果。尽管瘢痕疙瘩在普通人群中普遍存在，但它们仍然是较具挑战性的皮肤病之一，难以处理。瘢痕疙瘩不仅是一种美容上的麻烦，它们通常还伴有症状，会给患者带来重大的心理社会负担。虽然有多种治疗方式，但尚无单一治疗方法被证明具有广泛的有效性。事实上，治疗后复发通常是常态。联合治疗可能是最佳策略。在本综述中，我们重点介绍瘢痕疙瘩的临床特征、病理生理学和治疗方法。
