Borghesi A, Stronati M
Neonatal Intensive Care Unit, Fondazione IRCCS-Policlinico San Matteo, Pavia, Italy.
J Hosp Infect. 2008 Apr;68(4):293-300. doi: 10.1016/j.jhin.2008.01.011. Epub 2008 Mar 7.
Nosocomial infections are among the leading causes of mortality and morbidity in neonatal intensive care units. Prevention of healthcare-associated infections is based on strategies that aim to limit susceptibility to infections by enhancing host defences, interrupting transmission of organisms by healthcare workers and by promoting the judicious use of antimicrobials. Several strategies are available and include: hand hygiene practices; prevention of central venous catheter-related bloodstream infections; judicious use of antimicrobials for therapy and prophylaxis; enhancement of host defences; skin care; and early enteral feeding with human milk.
医院感染是新生儿重症监护病房死亡和发病的主要原因之一。医疗保健相关感染的预防基于旨在通过增强宿主防御、中断医护人员传播病原体以及促进抗菌药物的合理使用来限制感染易感性的策略。有几种策略可供选择，包括：手卫生措施；预防中心静脉导管相关血流感染；抗菌药物在治疗和预防中的合理使用；增强宿主防御；皮肤护理；以及尽早用母乳进行肠内喂养。
