Million Matthieu, Roux Fabienne, Cohen Solal Julien, Bréville Philippe, Desplaces Nicole, Barthas Jean, Nguyen Van Jean-Claude, Rajzbaum Gérald
Rheumatology Department, Groupe Hospitalier Paris Saint-Joseph, 185 rue Raymond Losserand, 75014 Paris, France.
Joint Bone Spine. 2008 May;75(3):356-8. doi: 10.1016/j.jbspin.2007.06.012. Epub 2008 Feb 12.
Propionibacterium avidum is a Gram-positive, nonsporulating, facultative anaerobe that has a low level of virulence and is rarely pathogenic. This ubiquitous inhabitant of the sebaceous glands and hair follicles can cause acne vulgaris. Very rarely, P. avidum causes systemic infections after invasive procedures, most notably in immunocompromised patients. Two cases of sacroiliitis due to P. avidum have been reported. We report a case of P. avidum arthritis of the hip with severe sepsis that developed in a 78-year-old woman after intraarticular glucocorticoid treatment for hip osteoarthritis. We are unaware of previous reports of P. avidum hip arthritis.
嗜丙酸杆菌是一种革兰氏阳性、不产芽孢的兼性厌氧菌，其毒力较低，很少致病。这种皮脂腺和毛囊中普遍存在的细菌可导致寻常痤疮。非常罕见的是，嗜丙酸杆菌在侵入性操作后会引起全身感染，最常见于免疫功能低下的患者。已有两例由嗜丙酸杆菌引起的骶髂关节炎的报道。我们报告一例78岁女性在接受髋关节骨关节炎关节内糖皮质激素治疗后发生的伴有严重脓毒症的嗜丙酸杆菌性髋关节炎病例。我们未发现此前有嗜丙酸杆菌性髋关节炎的报道。
