Lowe Nick J
Cranley Clinic, London, United Kingdom.
J Cosmet Laser Ther. 2008 Mar;10(1):43-6. doi: 10.1080/14764170701840074.
Injectable devices are less invasive than surgical interventions for restoring youthful contours. Sculptra (Dermik Laboratories, Bridgewater, NJ, USA, a business of sanofi aventis U.S. LLC) contains poly-l-lactic acid (PLLA), which is thought to elicit in vivo collagen production around the injected implant, producing new volume gradually over time, and with effects lasting up to 2 years. Correct reconstitution and preparation of PLLA, as well as injection technique, are essential to ensure optimal outcomes and reduce adverse events. This article provides an overview of injectable devices, specifically focusing on PLLA in cosmetic application and optimal administration techniques to maximize efficacy and duration of effect.
对于恢复年轻轮廓而言，可注射装置的侵入性低于手术干预。塑然雅（美国新泽西州布里奇沃特德密克实验室，赛诺菲安万特美国有限责任公司旗下业务）含有聚左旋乳酸（PLLA），据认为其可在注射植入物周围引发体内胶原蛋白生成，随着时间推移逐渐产生新的容积，效果可持续长达2年。正确复溶和配制PLLA以及注射技术对于确保获得最佳效果和减少不良事件至关重要。本文概述可注射装置，特别聚焦于PLLA在美容应用中的情况以及可使疗效和效果持续时间最大化的最佳给药技术。
