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老年医疗保险和医疗补助计划参保的结肠癌患者术后辅助化疗

Adjuvant chemotherapy after resection in elderly Medicare and Medicaid patients with colon cancer.

作者信息

Bradley Cathy J, Given Charles W, Dahman Bassam, Fitzgerald Timothy L

机构信息

Department of Health Administration and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298-0203, USA.

出版信息

Arch Intern Med. 2008 Mar 10;168(5):521-9. doi: 10.1001/archinternmed.2007.82.

Abstract

BACKGROUND

This study investigated the influence of Medicaid enrollment on the receipt and completion of adjuvant chemotherapy and the likelihood of evaluation by an oncologist for those patients who do not initiate chemotherapy.

METHODS

Medicaid and Medicare administrative data were merged with the Michigan Tumor Registry to extract a sample of patients who had resection for a first primary colon tumor diagnosed between January 1, 1997, and December 31, 2000 (n = 4765). We used unadjusted and adjusted logistic regression to assess the relationship between Medicaid enrollment and the outcomes of interest.

RESULTS

Relative to Medicare patients, Medicaid patients were less likely to initiate chemotherapy (odds ratio, 0.50; 95% confidence interval, 0.39-0.65) or complete chemotherapy (odds ratio, 0.52; 95% confidence interval, 0.31-0.85). When the sample was restricted to patients with TNM-staged disease, Medicaid patients were less likely to initiate chemotherapy. Older patients and patients with comorbidities were also less likely to initiate or, in some cases, to complete chemotherapy.

CONCLUSION

Medicaid enrollment is associated with disparate colon cancer treatment, which likely compromises the long-term survival of these patients.

摘要

背景

本研究调查了医疗补助计划参保情况对辅助化疗的接受和完成情况的影响,以及对那些未开始化疗的患者进行肿瘤学家评估的可能性。

方法

将医疗补助计划和医疗保险的管理数据与密歇根肿瘤登记处合并,以提取1997年1月1日至2000年12月31日期间首次原发性结肠癌切除患者的样本(n = 4765)。我们使用未调整和调整后的逻辑回归来评估医疗补助计划参保情况与感兴趣的结局之间的关系。

结果

相对于医疗保险患者,医疗补助计划患者开始化疗的可能性较小(比值比,0.50;95%置信区间,0.39 - 0.65)或完成化疗的可能性较小(比值比,0.52;95%置信区间,0.31 - 0.85)。当样本仅限于TNM分期疾病患者时,医疗补助计划患者开始化疗的可能性较小。老年患者和合并症患者开始化疗或在某些情况下完成化疗的可能性也较小。

结论

医疗补助计划参保情况与结肠癌治疗差异相关,这可能会损害这些患者的长期生存。

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