Suppr超能文献

钝性脾损伤:我们观察得够久了吗?

Blunt splenic injuries: have we watched long enough?

作者信息

Smith Jason, Armen Scott, Cook Charles H, Martin Larry C

机构信息

Department of Surgery, The Ohio State University, Columbus, Ohio, USA.

出版信息

J Trauma. 2008 Mar;64(3):656-63; discussion 663-5. doi: 10.1097/TA.0b013e3181650fb4.

Abstract

BACKGROUND

Nonoperative management (NOM) of blunt splenic injuries (BSIs) has been used with increasing frequency in adult patients. There are currently no definitive guidelines established for how long BSI patients should be monitored for failure of NOM after injury.

METHODS

This study was performed to ascertain the length of inpatient observation needed to capture most failures, and to identify factors associated with failure of NOM. We utilized the National Trauma Data Bank to determine time to failure after BSI.

RESULTS

During the 5-year study period, 23,532 patients were identified with BSI, of which 2,366 (10% overall) were taken directly to surgery (within 2 hours of arrival). Of 21,166 patients initially managed nonoperatively, 18,506 were successful (79% of all-comers). Patients with isolated BSI are currently monitored approximately 5 days as inpatients. Of patients failing NOM, 95% failed during the first 72 hours, and monitoring 2 additional days saw only 1.5% more failures. Factors influencing success of NOM included computed tomographic injury grade, severity of patient injury, and American College of Surgeons designation of trauma center. Importantly, patients who failed NOM did not seem to have detrimental outcomes when compared with patients with successful NOM. No statistically significant predictive variables could be identified that would help predict patients who would go on to fail NOM.

CONCLUSIONS

We conclude that at least 80% of BSI can be managed successfully with NOM, and that patients should be monitored as inpatients for failure after BSI for 3 to 5 days.

摘要

背景

钝性脾损伤(BSIs)的非手术治疗(NOM)在成年患者中的应用频率越来越高。目前尚无关于BSI患者受伤后应监测多长时间以确定非手术治疗失败的明确指南。

方法

本研究旨在确定捕获大多数治疗失败所需的住院观察时间,并确定与非手术治疗失败相关的因素。我们利用国家创伤数据库来确定BSI后治疗失败的时间。

结果

在为期5年的研究期间,共识别出23,532例BSI患者,其中2,366例(占总数的10%)直接接受手术治疗(到达后2小时内)。在最初接受非手术治疗的21,166例患者中,18,506例治疗成功(占所有患者的79%)。目前,单纯BSI患者住院观察约5天。在非手术治疗失败的患者中,95%在最初72小时内失败,再额外监测2天仅多发现1.5%的失败病例。影响非手术治疗成功的因素包括计算机断层扫描损伤分级、患者损伤严重程度以及美国外科医师学会指定的创伤中心。重要的是,与非手术治疗成功的患者相比,非手术治疗失败的患者似乎并未出现不良后果。未发现有统计学意义的预测变量可帮助预测哪些患者会出现非手术治疗失败。

结论

我们得出结论,至少80%的BSI可以通过非手术治疗成功处理,并且BSI患者受伤后应住院监测3至5天以确定治疗失败情况。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验