跨突触可塑性：突触前起始，突触后记忆。
Trans-synaptic plasticity: presynaptic initiation, postsynaptic memory.
作者信息
Wan Qin, Abrams Thomas W
机构信息
Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland 21201-1559, USA.
出版信息
Curr Biol. 2008 Mar 11;18(5):R220-3. doi: 10.1016/j.cub.2007.12.046.
PMID:18334201
Abstract
A novel mechanism of persistent facilitation induced by serotonin at Aplysia synapses depends upon rapid postsynaptic protein synthesis and increased responsiveness to glutamate; whereas the memory for this synaptic change is postsynaptic, the initiating signal may be an increase in spontaneous release of glutamate from the presynaptic terminals.
摘要
5-羟色胺在海兔突触处诱导持续性易化的一种新机制，依赖于快速的突触后蛋白质合成以及对谷氨酸盐反应性的增强；虽然这种突触变化的记忆是突触后的，但起始信号可能是突触前终末谷氨酸盐自发释放的增加。
Zotero 插件