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伴有免疫球蛋白水平升高和血小板增多症的婴儿骨皮质增生症

Caffey disease with raised immunoglobulin levels and thrombocytosis.

作者信息

Kumar T Sathish, Scott Julius Xavier, Mathew Leni Grace

机构信息

Child Health Unit 1, Christian Medical College, Vellore, India.

出版信息

Indian J Pediatr. 2008 Feb;75(2):181-2. doi: 10.1007/s12098-008-0027-4.

DOI:10.1007/s12098-008-0027-4
PMID:18334802
Abstract

Infantile cortical hyperostosis (Caffey disease) is characterized by radiological evidence of cortical hyperostosis, soft tissue swellings, fever and irritability. We report a case of Caffey disease highlighting its presentation with thrombocytosis and high serum immunoglobulin level to alert physicians to use steroids cautiously in view of the known thrombocythemic effect of the drug. Raised Immunoglobulin also suggests that this syndrome could be infectious in origin.

摘要

婴儿皮质增生症(卡菲病)的特征为皮质增生的影像学证据、软组织肿胀、发热及易激惹。我们报告一例卡菲病病例,强调其伴有血小板增多症及血清免疫球蛋白水平升高的表现,以提醒医生鉴于该药物已知的血小板增多效应而谨慎使用类固醇。免疫球蛋白升高也提示该综合征可能起源于感染。

相似文献

1
Caffey disease with raised immunoglobulin levels and thrombocytosis.伴有免疫球蛋白水平升高和血小板增多症的婴儿骨皮质增生症
Indian J Pediatr. 2008 Feb;75(2):181-2. doi: 10.1007/s12098-008-0027-4.
2
Infantile cortical hyperostosis.婴儿骨皮质增生症
Indian Pediatr. 2005 Jan;42(1):64-6.
3
Infantile cortical hyperostosis. Caffey disease.
Acta Paediatr Belg. 1976 Jul-Sep;29(3):185-8.
4
Raised immunoglobulin levels and thrombocytosis in infantile cortical hyperostosis.
Arch Dis Child. 1972 Dec;47(256):982-3. doi: 10.1136/adc.47.256.982.
5
Infantile cortical hyperostosis (Caffey disease): a possible misdiagnosis as physical abuse.婴儿皮质性骨肥厚(Caffey 病):可能误诊为虐待身体。
Hong Kong Med J. 2010 Oct;16(5):397-9.
6
[Neonatal Caffey-Silverman disease with thrombocytosis, increase in C-reactive protein and immunoglobulins].
Arch Fr Pediatr. 1988 Apr;45(4):263-5.
7
[Description of a case of infantile cortical hyperostosis with thrombocytemia and an increase of immunoglobulins].
Minerva Pediatr. 1984 Apr 30;36(8):417-20.
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Swelling over the face: infantile cortical hyperostosis.面部肿胀:婴儿皮质增生症。
Int J Pediatr Otorhinolaryngol. 1994 Apr;29(2):147-50. doi: 10.1016/0165-5876(94)90094-9.
9
Severe thrombocytosis as initial manifestation of Caffey disease in a 4 month old infant.4个月大婴儿中,严重血小板增多症作为卡菲病的初始表现。
Pediatr Blood Cancer. 2012 Aug;59(2):345-6. doi: 10.1002/pbc.24063. Epub 2011 Dec 27.
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Infantile cortical hyperostosis with raised immunoglobulins.伴有免疫球蛋白升高的婴儿皮质增生症。
Arch Dis Child. 1978 May;53(5):426-8. doi: 10.1136/adc.53.5.426.

引用本文的文献

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Fetal MRI and postnatal findings of severe infantile cortical hyperostosis: A case report of prenatal Caffey disease with literature review.重度婴儿皮质增生症的胎儿磁共振成像及产后表现:1例产前卡菲病病例报告并文献复习
Radiol Case Rep. 2025 Jun 24;20(9):4530-4535. doi: 10.1016/j.radcr.2025.05.070. eCollection 2025 Sep.
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Caffey's disease in disguise: a child abuse mimic.伪装下的卡费氏病:一种虐待儿童的模拟病。
BMJ Case Rep. 2024 Feb 7;17(2):e256998. doi: 10.1136/bcr-2023-256998.
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Caffey Disease in Infancy: A diagnostic dilemma for primary care physicians.

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1例用萘普生治疗的复发性婴儿骨皮质增生症。
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Raised immunoglobulin levels and thrombocytosis in infantile cortical hyperostosis.
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Infantile cortical hyperostosis associated with thrombocythaemia.婴儿皮质增生症伴血小板增多症
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Infantile cortical hyperostosis with raised immunoglobulins.伴有免疫球蛋白升高的婴儿皮质增生症。
Arch Dis Child. 1978 May;53(5):426-8. doi: 10.1136/adc.53.5.426.
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Virus diseases of bone. Do they exist? The Neuhauser Lecture.骨的病毒疾病。它们存在吗?纽豪泽讲座。
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