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布鲁氏菌病的不寻常表现:由羊布鲁氏菌引起的肝脓肿和全血细胞减少。

Unusual manifestation of brucellosis: liver abscess and pancytopenia caused by Brucella melitensis.

作者信息

Starakis Ioannis, Polyzogopoulou Eftichia, Siagris Dimitrios, Mazokopakis Elias, Gogos Charalambos A

机构信息

Department of Internal Medicine, Patras University Hospital, Rion-Patras, Greece.

出版信息

Eur J Gastroenterol Hepatol. 2008 Apr;20(4):349-52. doi: 10.1097/MEG.0b013e3282ef9493.

Abstract

Brucellosis is a zoonosis with a worldwide distribution, and still endemic in Greece. Although hepatic involvement is common, cholecystitis and hepatic abscesses represent rare complications of the disease. Hematological manifestations of brucellosis include various abnormalities such as anemia and leucopenia, but the disease rarely presents with pancytopenia. We present a case of liver abscess and pancytopenia caused by Brucella melitensis in a 54-year-old worker who consumed unpasteurized dairy products. The patient was admitted twice to our hospital and finally diagnosed as suffering from a gallbladder empyema complicated by a liver abscess, for which he underwent surgery. Blood cultures drawn on his second admission isolated Brucella melitensis. Repeated serum agglutination testing for brucella turned out negative.

摘要

布鲁氏菌病是一种分布于全球的人畜共患病,在希腊仍呈地方性流行。虽然肝脏受累很常见,但胆囊炎和肝脓肿是该疾病罕见的并发症。布鲁氏菌病的血液学表现包括各种异常,如贫血和白细胞减少,但该疾病很少表现为全血细胞减少。我们报告一例由羊种布鲁氏菌引起的肝脓肿和全血细胞减少病例,患者为一名54岁的工人,曾食用未经过巴氏消毒的乳制品。该患者两次入住我院,最终被诊断为胆囊积脓并发肝脓肿,并接受了手术治疗。其第二次入院时采集的血培养分离出羊种布鲁氏菌。布鲁氏菌反复血清凝集试验结果为阴性。

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