Yin Yong-Qin, Kong Ling-Yi
Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
J Asian Nat Prod Res. 2008 Mar-Apr;10(3-4):245-52. doi: 10.1080/10286020701604839.
Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataosides I and II have novel structures because the core simonic acid B was esterised with cinnamic acid for the first time, and three different substituent esterification groups in one resin glycoside is scarce. The absolute configuration of the aglycone was elucidated to be S by Mosher's method.
从甘薯的根中分离出两种新的树脂糖苷，即甘薯苷I（1）和II（2），以及五种已知化合物，分别为木栓酮（3）、东莨菪素（4）、十八烷基咖啡酸酯（5）、β-谷甾醇（6）和胡萝卜苷（7）。它们的结构已根据化学和光谱数据确定。甘薯苷I和II具有新颖的结构，因为核心的刺槐二糖酸B首次与肉桂酸发生酯化反应，并且在一种树脂糖苷中存在三个不同的取代酯化基团的情况很少见。通过Mosher方法阐明了苷元的绝对构型为S型。
