除肌肉和肝脏毒性外的贝特类药物相关不良反应。
Fibrate-associated adverse effects beyond muscle and liver toxicity.
作者信息
Florentin M, Liberopoulos E N, Mikhailidis D P, Elisaf M S
机构信息
Department of Internal Medicine, Medical School, University of Ioannina, Ioannina 45110, Greece.
出版信息
Curr Pharm Des. 2008;14(6):574-87. doi: 10.2174/138161208783885362.
PMID:18336300
Abstract
Fibrate derivatives have a 40-year history in the management of dyslipidemia. Although this class of drugs is generally well tolerated, several safety issues have arisen from their use. In the present article we review the literature describing side effects associated with the use of fibrates except for those that are liver and muscle related. These effects are less well known but are clinically relevant.
摘要
贝特类衍生物在血脂异常管理方面已有40年历史。尽管这类药物总体耐受性良好，但使用过程中出现了一些安全问题。在本文中，我们回顾了描述贝特类药物使用相关副作用的文献，但不包括与肝脏和肌肉相关的副作用。这些副作用鲜为人知，但具有临床相关性。
Zotero 插件