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腹膜透析中人口统计学、临床及生化参数与腹膜炎的关系

Relation of demographic, clinic and biochemical parameters to peritonitis in peritoneal dialysis.

作者信息

Dogan Sevel, Ekiz Serpil, Yucel Lamia, Ozturk Savas, Kazancioglu Rumeyza

机构信息

Haseki Training and Research Hospital, Nephrology Clinic, Istanbul, Turkey.

出版信息

J Ren Care. 2008 Mar;34(1):5-8. doi: 10.1111/j.1755-6686.2008.00003.x.

DOI:10.1111/j.1755-6686.2008.00003.x
PMID:18336516
Abstract

The relation of various demographic, clinical and biochemical parameters of peritoneal dialysis patients with peritonitis and other infections was evaluated. The age, gender, peritoneal dialysis (PD) period, educational status, peritonitis, exit site score, serum albumin, C-reactive protein (CRP), and triglyceride levels at the beginning and the last visit were recorded. Mean age of 32 patients was 45.1 years; PD period was 13.1 months. Albumin level was inversely proportional to the frequency of peritonitis. Patients with peritonitis had albumin levels that were lower at the last visit, and were independent of the CRP values at the start of PD and during follow-up. Significant correlation was detected between females and exit site scores. There was significant correlation between educational status and peritonitis. Albumin level at first visit was a factor that reduced the likelihood of peritonitis, and low levels obtained during follow-up constituted a risk for peritonitis. It was also shown that peritonitis risk tended to decrease inversely with education level.

摘要

评估了腹膜透析患者各种人口统计学、临床和生化参数与腹膜炎及其他感染之间的关系。记录了患者的年龄、性别、腹膜透析(PD)时间、教育程度、腹膜炎情况、出口处评分、血清白蛋白、C反应蛋白(CRP)以及首次就诊和末次就诊时的甘油三酯水平。32例患者的平均年龄为45.1岁;腹膜透析时间为13.1个月。白蛋白水平与腹膜炎发生频率呈负相关。发生腹膜炎的患者在末次就诊时白蛋白水平较低,且与腹膜透析开始时及随访期间的CRP值无关。女性与出口处评分之间存在显著相关性。教育程度与腹膜炎之间存在显著相关性。首次就诊时的白蛋白水平是降低腹膜炎发生可能性的一个因素,随访期间获得的低水平白蛋白构成腹膜炎发生风险。研究还表明,腹膜炎风险倾向于与教育程度呈反比降低。

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