Al-Saffar Nabeel, Abdulkareem Abdulraheem, Abdulhakeem Alsughayer, Salah Al-Qattan, Heba Metwalli
Department of Pharmaceutical Sciences, College of Health Sciences, PAAET, Kuwait.
Patient Educ Couns. 2008 Jul;72(1):94-101. doi: 10.1016/j.pec.2008.01.027. Epub 2008 Mar 11.
To assess patients' opinion toward receiving written or specialized verbal pharmacists' interventions and to determine the effect of these interventions on patients' medication knowledge.
150 newly diagnosed patients with unipolar depression and initiated with a single antidepressant were randomized into 3 groups: control, leaflet and counselling, and interviewed at initiation and after 6-8 weeks of treatment at the outpatient department of the Psychiatric Hospital in Kuwait.
50% of respondents asserted that clinicians did not give them sufficient information while 90% favoured the idea of receiving further information about therapy. Forty seven percent of participants failed to return for the second follow-up appointment. The drop-out rate was 66% in the control, 42% in the Leaflet and only 34% in the counselling groups (P=0.004). A broad support for receiving leaflets and drug counselling (97%) was found among attendees. Moreover, 94% of the counselling and 79% of the leaflets group affirmed that they received adequate information compared to 47% of the control (P=0.001). Counselling was found to be significantly associated with a much higher recall of medicine name (OR=9.6, P=0.01), how to manage missed doses (OR=8.9, P=0.007), and correct use of medication (OR=31.3, P<0.001). Leaflet use was less strongly associated than counselling and was statistically significant for recall regarding correct use of medication (OR=8.4, P=0.009).
Pharmacists in a psychiatric institution can play an important role in satisfying patient demands for specialized information about their medications. Patients with depression appear very eager to receive additional drug information with modest difference between the written and the verbal counselling interventions. Patients looked at the two interventions in a very positive manner and no difference was observed between patients in the leaflets and in the counselling group with regards to how helpful, sufficient, supportive and reassuring was the educational material. However, both interventions were more informative than the control in conveying elemental drug information to patients.
In contrast with the lack of enthusiasm that some clinicians express, the affirmativeness that was expressed by patients towards receiving written or verbal specialized educational interventions by pharmacists may support the psychiatric hospital pharmacists' stands in providing them for all patients which may aid in improving patients compliance and probably treatment outcome.
评估患者对接受书面或专业口头药剂师干预的看法,并确定这些干预对患者用药知识的影响。
150名新诊断为单相抑郁症且开始使用单一抗抑郁药的患者被随机分为3组:对照组、传单组和咨询组,并在科威特精神病医院门诊部治疗开始时及治疗6 - 8周后进行访谈。
50%的受访者称临床医生未给予他们足够信息,而90%的受访者赞成获取更多关于治疗的信息。47%的参与者未返回进行第二次随访预约。对照组的退出率为66%,传单组为42%,咨询组仅为34%(P = 0.004)。在参与者中发现对获取传单和药物咨询有广泛支持(97%)。此外,咨询组的94%和传单组的79%确认他们获得了足够的信息,而对照组为47%(P = 0.001)。发现咨询与药物名称的更高回忆率(OR = 9.6,P = 0.01)、如何处理漏服剂量(OR = 8.9,P = 0.007)以及正确用药(OR = 31.3,P < 0.001)显著相关。传单的使用与咨询的相关性较弱,在正确用药回忆方面具有统计学意义(OR = 8.4,P = 0.009)。
精神病机构的药剂师在满足患者对其药物专业信息的需求方面可发挥重要作用。抑郁症患者似乎非常渴望获得更多药物信息,书面和口头咨询干预之间差异不大。患者对这两种干预持非常积极的态度,在教育材料的帮助性、充分性、支持性和安心程度方面,传单组和咨询组的患者之间未观察到差异。然而,在向患者传达基本药物信息方面,两种干预都比对照组更具信息性。
与一些临床医生表现出的缺乏热情相反,患者对接受药剂师的书面或口头专业教育干预所表达的肯定态度,可能支持精神病医院药剂师为所有患者提供这些干预的立场,这可能有助于提高患者的依从性,并可能改善治疗结果。