Ansari Khalid, Dalal Kuldeep, Patel Mayur
Department of Critical Care, Jaslok Hospital and Research Centre, Mumbai.
J Indian Med Assoc. 2007 Sep;105(9):536, 538, 540 passim.
To assess the risk for venous thrombo-embolism (VTE) and the utilisation of VTE prophylaxis in an open medical-surgical intensive care unit (ICU), patients were admitted and enrolled to the ICU at a multispecialty, tertiary care teaching hospital in Mumbai, for an observational study during a 3-month period. Risk factors for VTE and methods of VTE prophylaxis used were noted. Risk stratification was done, and the consultants attending the ICUs filled a questionnaire about VTE awareness, preferences and usage of VTE prophylaxis methods and reasons for not using thromboprophylaxis. Of 580 admissions, 488 were included in the study. As per the risk stratification, thromboprophylaxis was indicated in 466 (95%). The study group had an average VTE risk of 5.74, with a mean risk of 6.48 in medical patients and 5.0 in surgical patients. The most common risk factors in medical patients were bed rest >72 hours (56%), age >60 years (49.6%) and age 40-60 years (38.4%). Among surgical patients, the most common risk factors were major surgery (80.25%), central venous access (59.24%) and age 40-60 years (46.6%). Overall, VTE prophylaxis was used in 229 patients (47%), with 127 (55%) medical and 102 (45%) surgical patients. The most common methods of VTE prophylaxis used were elastic stockings (24.2%), low molecular weight heparin (15%) and low molecular weight heparin and stockings both (9.6%). Fear of bleeding was the commonest reason cited for the underutilisation of VTE prophylaxis. Almost half of all high-risk patients admitted to the ICU didn't receive any thromboprophylaxis. Consistent practice patterns of ICUs, and continuing medical education programmes addressing VTE prophylaxis will help improve the usage of VTE prophylaxis.
为评估一家开放式内科-外科重症监护病房(ICU)中静脉血栓栓塞(VTE)的风险及VTE预防措施的使用情况,在孟买一家多专科三级护理教学医院的ICU对患者进行收治并纳入观察性研究,为期3个月。记录VTE的风险因素及所采用的VTE预防措施。进行风险分层,ICU的会诊医生填写一份关于VTE认知、VTE预防措施的偏好和使用情况以及未使用血栓预防措施原因的问卷。在580例入院患者中,488例被纳入研究。根据风险分层,466例(95%)患者需要进行血栓预防。研究组的平均VTE风险为5.74,内科患者的平均风险为6.48,外科患者为5.0。内科患者最常见的风险因素是卧床休息>72小时(56%)、年龄>60岁(49.6%)和40 - 60岁(38.4%)。外科患者中,最常见的风险因素是大手术(80.25%)、中心静脉置管(59.24%)和40 - 60岁(46.6%)。总体而言,229例患者(47%)使用了VTE预防措施,其中内科患者127例(55%),外科患者102例(45%)。最常用的VTE预防措施是弹力袜(24.2%)、低分子肝素(15%)以及低分子肝素和弹力袜联合使用(9.6%)。担心出血是VTE预防措施使用不足最常提及的原因。几乎一半入住ICU的高危患者未接受任何血栓预防措施。ICU的一致实践模式以及针对VTE预防的继续医学教育项目将有助于提高VTE预防措施的使用率。