Laffaye Charlene, McKellar John D, Ilgen Mark A, Moos Rudolf H
Center for Health Care Evaluation, Veterans Affairs Palo Alto Health Care System, Menlo Park, CA 94025, USA.
Addiction. 2008 Apr;103(4):671-80. doi: 10.1111/j.1360-0443.2008.02147.x.
This study examined systematically how predictors of substance use disorder (SUD) treatment outcome worked together over time and identified mediators and moderators of outcome.
The MacArthur model was applied in this naturalistic study to identify how baseline, discharge and 1-year follow-up factors worked together to predict 4-year improvement in substance-related problems.
Eighty-eight community residential facilities were selected based on geographic representativeness, number of patient referrals and type of treatment orientation.
Of 2796 male patients who completed intake assessments, 2324 were assessed at the 1-year follow-up and 2023 at the 4-year follow-up.
Self-report measures of symptom severity, functioning, social resources and coping, treatment and involvement in Alcoholics Anonymous (AA) were collected at baseline and at 1- and 4-year follow-ups. Provider-rated treatment participation measures were obtained at discharge.
Greater substance use severity, more psychiatric symptoms, more prior arrests and stronger belief in AA-related philosophy at treatment entry predicted improvement significantly in substance-related problems 4 years later. At the 1-year follow-up, being employed and greater use of AA-related coping predicted outcome significantly. AA-related coping at 1 year mediated the relationship partially between belief in AA philosophy at treatment entry and 4-year outcome.
The findings highlight the unique and positive impact of AA involvement on long-term SUD treatment outcome and extend understanding of why AA is beneficial for patients.
本研究系统考察了物质使用障碍(SUD)治疗结果的预测因素如何随时间共同起作用,并确定了结果的中介因素和调节因素。
在这项自然主义研究中应用了麦克阿瑟模型,以确定基线、出院和1年随访因素如何共同作用来预测与物质相关问题的4年改善情况。
根据地理代表性、患者转诊数量和治疗方向类型,选择了88个社区居住设施。
在2796名完成入院评估的男性患者中,2324人在1年随访时接受了评估,2023人在4年随访时接受了评估。
在基线、1年和4年随访时收集了关于症状严重程度、功能、社会资源和应对方式、治疗以及参与戒酒互助会(AA)的自我报告测量数据。在出院时获得了提供者评定的治疗参与度测量数据。
治疗开始时物质使用严重程度更高、精神症状更多、既往被捕次数更多以及对与AA相关理念的信念更强,显著预测了4年后与物质相关问题的改善情况。在1年随访时,就业和更多地使用与AA相关的应对方式显著预测了结果。1年时与AA相关的应对方式部分介导了治疗开始时对AA理念的信念与4年结果之间的关系。
研究结果突出了参与AA对SUD长期治疗结果的独特积极影响,并扩展了对AA为何对患者有益的理解。