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曲马多与地塞米松作为布比卡因合剂用于锁骨上臂丛神经阻滞的比较研究

Comparative study between tramadol and dexamethasone as an admixture to bupivacaine in supraclavicular brachial plexus block.

作者信息

Shrestha B R, Maharjan S K, Shrestha S, Gautam B, Thapa C, Thapa P B, Joshi M R

机构信息

Department of Anaesthesiology, Kathmandu Medical College, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2007 Oct-Dec;46(168):158-64.

Abstract

This is a prospective, randomized, double blind study to evaluate the postoperative analgesia following supraclavicular brachial plexus block with Tramadol or Dexamethasone as an admixture to bupivacaine in upper extremity surgery. Total 60 patients of ASA I and II undergoing upper extremity surgery under brachial plexus block with Bupivacaine were randomly divided in to two groups; one group received Tramadol (2 mg/kg) and the other group received Dexamethasone (8 mg) as an admixture to Bupivacaine. The duration of postoperative analgesia was recorded in both groups using pain VAS score which was determined by maximum VAS score of 8-10 and when patient demands for additional analgesics. The mean duration of postoperative analgesia in the Dexamethasone group was 1028.00 minutes while in the tramadol group it was 453.17 minutes We concluded that Dexamethasone with local anaesthetic prolongs postoperative analgesia significantly than Tramadol (P<0.05) when used as admixture to local anaesthetic in brachial plexus block in upper extremity surgery.

摘要

这是一项前瞻性、随机、双盲研究,旨在评估在臂丛神经阻滞中,将曲马多或地塞米松作为布比卡因的添加剂用于上肢手术时的术后镇痛效果。总共60例接受布比卡因臂丛神经阻滞下上肢手术的ASA I级和II级患者被随机分为两组;一组接受曲马多(2mg/kg),另一组接受地塞米松(8mg)作为布比卡因的添加剂。使用疼痛视觉模拟评分(VAS)记录两组的术后镇痛持续时间,该评分由8 - 10的最大VAS评分以及患者要求追加镇痛药时确定。地塞米松组术后镇痛的平均持续时间为1028.00分钟,而曲马多组为453.17分钟。我们得出结论,在上肢手术的臂丛神经阻滞中,当地塞米松与局部麻醉药混合使用时,其术后镇痛时间显著长于曲马多(P<0.05)。

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