Lee M L, Cooper A
Department of Dermatology, Royal North Shore Hospital, St Leonards, NSW.
Australas J Dermatol. 1991;32(1):17-20. doi: 10.1111/j.1440-0960.1991.tb00675.x.
Isotretinoin is a well-established, effective treatment for severe nodulocystic acne. An important consideration which may limit the prescription of isotretinoin is its cost. Based on a literature review, we have compared isotretinoin with the conventional combination of antibiotics and topical therapies for the treatment of severe nodulocystic acne in terms of cost and benefit. Our results show that when duration of treatment is considered, isotretinoin is cheaper and significantly more effective.
异维A酸是一种公认的、治疗重度结节囊肿性痤疮的有效药物。可能限制异维A酸处方的一个重要因素是其成本。基于文献综述，我们在成本和效益方面，将异维A酸与抗生素和局部治疗的传统组合用于治疗重度结节囊肿性痤疮进行了比较。我们的结果表明，考虑到治疗时长，异维A酸更便宜且显著更有效。
