Latash M L, Corcos D M
Department of Physiology, Rush-Presbyterian St. Luke's Medical Center, Chicago, IL 60612.
Am J Ment Retard. 1991 Sep;96(2):189-201.
Single-joint elbow flexion movements over different distances were performed "as fast as possible" by 10 subjects with Down syndrome and 6 control subjects. Kinematic parameters and electromyograms (EMGs) of major muscle groups were recorded. Muscle reactions to unexpected perturbations were recorded under different instructions. Four of the subjects with Down syndrome were able to demonstrate kinematic and EMG patterns typical for one of the basic strategies observed in the general population. Only one of the subjects with Down syndrome was able to modulate the "pre-programmed" reactions to unexpected perturbations. We conclude that there are no major qualitative deficits in the motor control mechanisms of individuals with Down syndrome, but there might be problems with proper modulation of motor commands.
10名唐氏综合征患者和6名对照受试者以“尽可能快”的速度进行了不同距离的单关节肘部屈曲运动。记录了主要肌肉群的运动学参数和肌电图（EMG）。在不同指令下记录了肌肉对意外扰动的反应。4名唐氏综合征患者能够表现出一般人群中观察到的一种基本策略所特有的运动学和肌电图模式。只有1名唐氏综合征患者能够调节对意外扰动的“预编程”反应。我们得出结论，唐氏综合征患者的运动控制机制没有重大的质性缺陷，但在运动指令的适当调节方面可能存在问题。
