McSweeney K, O'Connor D W
Aged Mental Health Research Unit, School of Psychology, Psychiatry and Psychological Medicine, Monash University, VIC, Australia.
Int Psychogeriatr. 2008 Aug;20(4):724-37. doi: 10.1017/S104161020800700X. Epub 2008 Mar 17.
This research concerns the prevalence and course of depression in newly admitted nursing home residents. We attempted to recruit consecutive admissions into the study, irrespective of cognitive status, enabling a comparison of the prevalence and course of depression experienced by cognitively intact residents and those exhibiting all levels of cognitive impairment.
Depression was assessed at one month, three months and six months post-admission. The assessment of mood in this study entailed the conduct of a semi-structured clinical interview, which encompassed DSM-IV criteria and Cornell Scale for Depression in Dementia (CSDD) items.
Recruitment difficulties resulted in a sample of 51 newly admitted residents, drawn from six nursing homes located in Victoria, Australia. Of particular interest, throughout the duration of the study, only the cognitively impaired were diagnosed with major depression (MD). One month post-admission, 24% of the sample were diagnosed with MD, and a further 20% evidenced a non-major depressive disorder. At the second and third assessments, MD was observed in 14% and 15% of residents, respectively. For residents who completed all three assessments, there was no appreciable change in the proportion diagnosed with a depressive disorder, nor was there a change in the levels of depressive symptomatology.
Although subject to limitations, the current study indicated that clinical depression in nursing home facilities most often occurs in residents who also exhibit pronounced cognitive impairment. These depressions are unlikely to remit spontaneously. Accordingly, care staff and general practitioners must be trained in the identification of depression in dementia, and any interventions implemented in these facilities should be tailored to meet the unique needs of this group.
本研究关注新入住养老院居民中抑郁症的患病率及病程。我们试图招募连续入院的居民参与研究,无论其认知状态如何,以便比较认知功能完好的居民与表现出不同程度认知障碍的居民所经历的抑郁症患病率及病程。
在入院后1个月、3个月和6个月对抑郁症进行评估。本研究中对情绪的评估需要进行半结构化临床访谈,其中涵盖了《精神疾病诊断与统计手册》第四版(DSM-IV)标准以及痴呆抑郁量表(CSDD)项目。
由于招募困难,最终样本为来自澳大利亚维多利亚州六家养老院的51名新入住居民。特别值得注意的是,在整个研究期间,只有认知受损的居民被诊断为重度抑郁症(MD)。入院1个月时,24%的样本被诊断为MD,另有20%表现为非重度抑郁障碍。在第二次和第三次评估中,分别有14%和15%的居民被观察到患有MD。对于完成了所有三次评估的居民,被诊断患有抑郁症的比例没有明显变化,抑郁症状水平也没有变化。
尽管存在局限性,但当前研究表明,养老院设施中的临床抑郁症最常发生在同时表现出明显认知障碍的居民中。这些抑郁症不太可能自发缓解。因此,护理人员和全科医生必须接受痴呆症患者抑郁症识别方面的培训,并且在这些设施中实施的任何干预措施都应根据该群体的独特需求进行调整。