Jeon Yun-Hee, Li Zhicheng, Low Lee-Fay, Chenoweth Lynn, O'Connor Daniel, Beattie Elizabeth, Liu Zhixin, Brodaty Henry
Sydney Nursing School, the University of Sydney, Sydney, Australia.
Sydney Nursing School, the University of Sydney, Sydney, Australia.
Am J Geriatr Psychiatry. 2015 Aug;23(8):784-93. doi: 10.1016/j.jagp.2014.08.013. Epub 2014 Sep 3.
To examine the clinical utility of the Cornell Scale for Depression in Dementia (CSDD) in nursing homes.
14 nursing homes in Sydney and Brisbane, Australia.
92 residents with a mean age of 85 years.
Consenting residents were assessed by care staff for depression using the CSDD as part of their routine assessment. Specialist clinicians conducted assessment of depression using the Semi-structured Clinical Diagnostic Interview for DSM-IV-TR Axis I Disorders for residents without dementia or the Provisional Diagnostic Criteria for Depression in Alzheimer Disease for residents with dementia to establish expert clinical diagnoses of depression. The diagnostic performance of the staff completed CSDD was analyzed against expert diagnosis using receiver operating characteristic (ROC) curves.
The CSDD showed low diagnostic accuracy, with areas under the ROC curve being 0.69, 0.68 and 0.70 for the total sample, residents with dementia and residents without dementia, respectively. At the standard CSDD cutoff score, the sensitivity and specificity were 71% and 59% for the total sample, 69% and 57% for residents with dementia, and 75% and 61% for residents without dementia. The Youden index (for optimizing cut-points) suggested different depression cutoff scores for residents with and without dementia.
When administered by nursing home staff the clinical utility of the CSDD is highly questionable in identifying depression. The complexity of the scale, the time required for collecting relevant information, and staff skills and knowledge of assessing depression in older people must be considered when using the CSDD in nursing homes.
探讨痴呆抑郁量表(CSDD)在养老院中的临床应用价值。
澳大利亚悉尼和布里斯班的14家养老院。
92名平均年龄85岁的居民。
作为常规评估的一部分,由护理人员使用CSDD对同意参与的居民进行抑郁评估。对于无痴呆的居民,专科临床医生使用《DSM-IV-TR轴I障碍的半结构化临床诊断访谈》进行抑郁评估;对于患有痴呆的居民,使用《阿尔茨海默病抑郁的临时诊断标准》进行评估,以建立抑郁的专家临床诊断。使用受试者工作特征(ROC)曲线分析护理人员完成的CSDD的诊断性能与专家诊断的对比情况。
CSDD显示出较低的诊断准确性,总样本、患有痴呆的居民和无痴呆的居民的ROC曲线下面积分别为0.69、0.68和0.70。在CSDD的标准临界值时,总样本的敏感性和特异性分别为71%和59%,患有痴呆的居民为69%和57%,无痴呆的居民为75%和61%。约登指数(用于优化切点)表明,患有痴呆和无痴呆的居民的抑郁临界值不同。
当由养老院工作人员实施时,CSDD在识别抑郁方面的临床应用价值高度存疑。在养老院使用CSDD时,必须考虑量表的复杂性、收集相关信息所需的时间以及工作人员评估老年人抑郁的技能和知识。