Feng Li, Ren Jin-ma, Zhang Jian, Yang Yue-jin, Huang Wen-li, Yang Chong-fu, Ye Shao-dong, Li Chong-jian, Yu Meng-yue, Ren Xiao-qing, Gao Xin, Luo Tong, Yuan Jian-Song, Li Bei-xiang, Yang Lin, Gong Jing, Teng Si-yong, Gu Dong-feng, Zeng Guang, Pu Jie-lin
Cardiac Arrhythmia Center, Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100037, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2007 Dec;35(12):1155-8.
The purpose of this study was to analyze the electrocardiographic features of the people living in the area with high incidence of unexplained sudden deaths in Yunnan province.
The electrocardiograms of 338 residents from three villages (Dayao, Ninglang, Heqing) with high incidence of unexplained sudden deaths and one control village (Dali) were analyzed [averaged age was (33.4 +/- 11.7) years, 175 men and 163 women].
The incidence of cardiac arrhythmias was similar low in all groups. The left ventricular hypertrophy was observed in 34.6% of residents from Dayao. QTc significantly prolonged in the residents from all 3 high incidence areas compare the control area of Dali [control (386.8 +/- 27.22) ms, Ninglang (428.92 +/- 25.71) ms, Heqing (440.67 +/- 28.03) ms, Dayao (417.7 +/- 24.00) ms, P < 0.05 vs. control]. Incidence of U wave was significantly higher in Heqing village than that in control village (P < 0.05). The QUc of these 3 villages was: (613.67 +/- 37.34) ms, (597.19 +/- 46.47) ms, (608.59 +/- 39.59) ms respectively, and also significantly longer than the control village of Dali (589.33 +/- 41.27) ms (P < 0.05). The typical pattern of U wave presents as enlarged U wave and apparent T-U complex. In the 7 residents who have the family history of unexplained sudden death, 6 residents have U wave, and 4 of them present typical U wave pattern.
The significant ECG changes in villages with high incidence of unexplained sudden death in Yunnan province were prolonged QTc, enlarged U wave and apparent T-U complex and these ECG features suggested the repolarization abnormalities of the heart in these subjects.
本研究旨在分析云南省不明原因猝死高发地区人群的心电图特征。
分析了来自不明原因猝死高发的三个村庄（大姚、宁蒗、鹤庆）和一个对照村庄（大理）的338名居民的心电图[平均年龄为(33.4±11.7)岁，男性175名，女性163名]。
所有组中心律失常的发生率均较低。大姚34.6%的居民存在左心室肥厚。与大理对照地区相比，所有3个高发地区居民的QTc均显著延长[对照(386.8±27.22)毫秒，宁蒗(428.92±25.71)毫秒，鹤庆(440.67±28.03)毫秒，大姚(417.7±24.00)毫秒，与对照相比P<0.05]。鹤庆村U波发生率显著高于对照村(P<0.05)。这3个村庄的QUc分别为：(613.67±37.34)毫秒、(597.19±46.47)毫秒、(608.59±39.59)毫秒，也显著长于大理对照村(589.33±41.27)毫秒(P<0.05)。U波的典型表现为U波增大和明显的T-U复合波。在有不明原因猝死家族史的7名居民中，6名有U波，其中4名呈现典型的U波模式。
云南省不明原因猝死高发村庄的显著心电图变化为QTc延长、U波增大和明显的T-U复合波，这些心电图特征提示这些受试者存在心脏复极异常。
