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[我在康索医院使用依法利珠单抗的临床经验]

[My clinical experience with efalizumab in the Hospital of Conxo].

作者信息

Vázquez-Veiga H A, Seoane-Pose M J, Fernández-Blanco M T

机构信息

Servicio de Dermatología, Hospital de Conxo, Complexo Hospitalario Universitario de Santiago de Compostela, A Coruña, España.

出版信息

Actas Dermosifiliogr. 2008 Jan;99 Suppl 1:62-9. doi: 10.1016/s0001-7310(08)76199-4.

Abstract

Psoriasis in plaques is a chronic disease that requires systemic treatment in its moderate and severe forms. Because the need for treatment is generally prolonged, many medications indicated for its treatment cannot be used continuously and have to be replaced by other different drugs, but also with a limited use, both due to their possible side effects, their teratogenicity, the time of use and accumulated dose, among other reasons. The biological drugs have been designed for middle and long term control of the disease. Efalizumab is a drug that has been shown to be effective and safe in patients who have moderate-to-severe psoriasis. We present our results in a group of 50 patients, our special cases, the form in which we have treated the side effects due to Efalizumab and those due to the disease.

摘要

斑块状银屑病是一种慢性疾病,中重度病例需要进行全身治疗。由于治疗需求通常持续时间较长,许多用于治疗该病的药物不能持续使用,必须换用其他不同药物,但即便如此其使用也受到限制,原因包括可能的副作用、致畸性、使用时间和累积剂量等。生物药物旨在对该病进行中长期控制。依法利珠单抗已被证明对中重度银屑病患者有效且安全。我们展示了对50例患者的治疗结果、特殊病例,以及我们处理依法利珠单抗所致副作用和疾病所致副作用的方式。

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