Livory M, Descamps V, Pelletier F, Maubec E, Faivre B, Marinho E, Humbert P, Crickx B, Aubin F
Service de dermatologie, hôpital Bichat, université Denis-Diderot Paris-7, Assistance publique-Hôpitaux de Paris, 46, rue Henri-Huchard, 75018 Paris, France.
Ann Dermatol Venereol. 2008 Jan;135(1):48-52. doi: 10.1016/j.annder.2007.01.001. Epub 2008 Jan 16.
Diagnosis of naevus lesions may be complex where they contain little or no pigmentation. Naevus spilus (or naevus on naevus) is, generally, readily identified by the difference in pigmentation between overlying and underlying naevi and healthy skin. Malignant transformation of naevus spilus is rare. We report two cases of melanoma in which surgical procedures revealed underlying melanocyte lesions, diagnosed at histology but undetectable on clinical examination.
Two patients were operated for melanoma in which surgery, at a site remote from the melanoma, suggested incomplete relapse despite the fact that previous clinical examination had indicated healthy skin. A diagnosis was made of melanoma in invisible naevus spilus.
Diagnosis of melanoma in invisible naevus spilus may be suspected where several naevi are found together in a specific area. The main problem is the therapeutic stance to be adopted since complete excision of the underlying naevi is difficult in practice. Wood's light examination may be helpful.
当痣病变几乎没有色素沉着或完全没有色素沉着时,其诊断可能较为复杂。斑痣(或痣上痣)通常可通过覆盖的痣与下方的痣以及健康皮肤之间色素沉着的差异轻易识别。斑痣的恶性转化很少见。我们报告了两例黑色素瘤病例,手术过程中发现了潜在的黑素细胞病变,这些病变在组织学上得以诊断,但临床检查无法检测到。
两名患者接受了黑色素瘤手术,在远离黑色素瘤的部位进行手术时,尽管之前的临床检查显示皮肤健康,但手术结果提示有不完全复发。诊断为隐匿性斑痣中的黑色素瘤。
在特定区域发现多个痣聚集在一起时,可能会怀疑隐匿性斑痣中的黑色素瘤。主要问题在于应采取的治疗立场,因为实际上很难完全切除潜在的痣。伍德灯检查可能会有所帮助。