Brufau C, Moran M, Armijo M
Ann Dermatol Venereol. 1986;113(5):409-18.
There is some doubt as to whether naevus pilus is identical with naevus-on-naevus or lentiginous naevus en mottes. The former could be classified together with Becker's naevus among the clinically progressive types of epidermal naevi, whereas the latter could be a truly melanocytic naevus of special expression which, for some authors, might become malignant. Seven cases of naevus-on-naevus with different sizes and locations are reported. In 3 cases the naevus was associated with other pathologies: pigmented sclerotic and kyphoscoliosis, verrucoid epidermal naevus, tuberous angioma and underlying muscular hypertrophy. In every case the diagnosis was confirmed by histological examination. An invasive malignant melanoma on superficial extensive melanoma coexisted with a retiform intradermal naevus pilosus. The hypothesis of complex neuro-ectodermic dysplasia and the histogenesis of malignant melanoma developed upon a naevus-on-naevus are discussed.
毛囊痣是否与痣上痣或斑状雀斑样痣相同存在一些疑问。前者可与贝克尔痣一起归类为临床上进行性的表皮痣类型,而后者可能是一种特殊表现的真正黑素细胞痣,对一些作者来说,它可能会恶变。报告了7例不同大小和部位的痣上痣病例。3例中该痣与其他病变相关:色素沉着性硬化和脊柱后凸侧弯、疣状表皮痣、结节状血管瘤及潜在的肌肉肥大。每例均经组织学检查确诊。浅表广泛黑色素瘤中的侵袭性恶性黑色素瘤与网状真皮内毛囊痣共存。讨论了复杂神经外胚层发育异常的假说以及痣上痣发生恶性黑色素瘤的组织发生。